2013年-2016年头孢类抗菌药物临床用药分析

发布时间：2018-12-28 10:23

【摘要】：目的探讨医院常用头孢类抗菌药物用药现状和趋势,旨在为头孢类抗菌药物合理使用提供指导意见。方法选取医院药学部药品库计算机管理系统提供的2013年6月-2016年5月常用头孢类抗菌药物使用数据,对常用头孢类抗菌药物销售数量、销售金额、构成比以及用药频度(DDDs)等情况进行统计分析。结果医院2013年6月-2016年5月各年度头孢类抗菌药物中常用药品销售金额中首位为头孢硫脒注射液,三个年度头孢硫脒注射液销售金额分别为4287394.4、6917626.9、4584950.4万元,其分别占35.1%、45.4%和31.6%;头孢硫脒注射液销售数量以及比例均处于首位,头孢硫脒、头孢唑林以及头孢哌酮舒巴坦排序均靠前;2013年6月-2016年5月各年度中头孢硫脒注射液B/A(销售金额排序序号B/DDDs排序序号A)均为1(1/1,1/1,1/1),2014年5月-2016年5月头孢替安、头孢哌酮舒巴坦B/A比值接近1(6/6,4/3)、(2/2,3/2)。结论医院头孢类抗菌药物使用趋于合理和规范化,然而个别品种依然存在过度使用的情况,所以还需进一步加强抗菌药物的使用管理,以便促进临床用药有效、经济和合理。
[Abstract]:Objective to explore the current situation and trend of cephalosporal antimicrobial drugs used in hospitals in order to provide guidance for rational use of cephalosporal antimicrobial agents. Methods the data of the use of commonly used cephalosporal antimicrobial drugs from June 2013 to May 2016, which were provided by the computer management system of drug bank of the Department of Pharmacy of Hospital, were selected, and the quantity and amount of sale of commonly used cephalosporal antibiotics were analyzed. Composition ratio and drug frequency (DDDs) were statistically analyzed. Results from June 2013 to May 2016, Cefathiamidine injection was the first common drug in the sales of cefathiraz in each year. The sales amount of cefathiamidine injection in three years was 4287394.4A6917626.9, 45.849504 billion yuan, respectively. It accounted for 45.4% and 31.6% respectively; The sales quantity and proportion of cefthiamidine injection were in the first place, cefathiamidine, cefazolin and cefoperazone sulbactam ranked first. From June 2013 to May 2016, Cefathiamidine injection B / A (sales amount sequence number B/DDDs sequence number A) was 1 (1 / 1 / 1 / 1 / 1 / 1 / 1 / 1 / 1), May 2014 to May 2016, cefatian, The cefoperazone sulbactam B / A ratio was close to 1 (6 / 6 / 4 / 3), (2 / 2 / 2 / 2). Conclusion the use of cephalosporins in hospitals tends to be reasonable and standardized, but there are still some cases of overuse in individual varieties. Therefore, it is necessary to further strengthen the management of the use of antimicrobial agents in order to promote the effective, economical and rational use of clinical antibiotics.
【作者单位】：绍兴市上虞中医医院药剂科;
【基金】：浙江省药学会医院药学科研基金资助项目(YJ2015-13)
【分类号】：R978.1

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