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抗结核药致药物超敏反应综合征2例报道

发布时间:2019-03-30 08:37
【摘要】:正药物超敏反应综合征(DIHS)是一种以急性广泛的皮损,伴发热、淋巴结肿大、多脏器受累(肝炎、肾炎、肺炎),嗜酸性粒细胞增多等血液异常为特征的严重全身性药物反应。1临床资料病例1,男,23岁。2012年2月13日诊断继发型右上肺结核(空洞)涂片阳性初治,予以常规剂量异烟肼、利福平、吡嗪酰胺、乙胺丁醇抗结核治疗。2012年3月9日因发热,皮疹3d入院。入院体检:体温39.0℃,全身红色麻疹样皮疹,双侧颈
[Abstract]:Positive drug hypersensitivity syndrome (DIHS) is characterized by acute extensive lesions with fever, enlarged lymph nodes and multiple organ involvement (hepatitis, nephritis, pneumonia). Severe systemic drug reactions characterized by blood abnormalities such as eosinophilia. 1 Clinical data case 1, male, 23 years old. Diagnosis of secondary upper right pulmonary tuberculosis (cavity) smear positive initial treatment, Feb. 13, 2012. Routine doses of isoniazid, rifampicin, pyrazinamide and ethambutol were given to patients with tuberculosis and were admitted to hospital for 3 days due to fever on March 9, 2012. Admission physical examination: body temperature 39.0 鈩,

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