长期口服地塞米松致1例医源性库欣综合征患者的药学监护
发布时间：2019-05-03 19:05
【摘要】：目的探讨临床药师参与糖皮质激素引起医源性库欣综合征药物治疗的作用。方法临床药师对1例口服地塞米松片长达10年,继发医源性库欣综合征、糖尿病等疾病的患者提出处置分析建议和药学监护。结果与结论患者逐渐减量至停用地塞米松片,改为醋酸氢化可的松20 mg,bid替代治疗,减药过程中未出现停药反应及反跳现象,对伴发疾病进行对应治疗后予以出院。临床药师在提高患者用药准确性方面具有重要作用,且有助于避免患者药源性药物不良反应的发生及不必要的经济负担。
[Abstract]:Objective to investigate the role of clinical pharmacists in the treatment of iatrogenic Cushing syndrome induced by glucocorticoid. Methods A patient with iatrogenic Cushing's syndrome and diabetes mellitus was treated with oral dexamethasone tablets for 10 years. Results and conclusion the patients gradually reduced to the discontinuation of dexamethasone tablets and were replaced with hydrocortisone acetate 20 mg,bid replacement therapy. There was no withdrawal reaction and rebound phenomenon in the course of drug reduction. The patients were discharged from the hospital after corresponding treatment for the associated diseases. Clinical pharmacists play an important role in improving the accuracy of drug use and help to avoid the occurrence of drug-induced adverse drug reactions and unnecessary economic burden.
【作者单位】： 首都医科大学附属北京朝阳医院药事部;南京大学医学院附属南京鼓楼医院药学部;
【分类号】：R977.1
本文编号：2469191
[Abstract]:Objective to investigate the role of clinical pharmacists in the treatment of iatrogenic Cushing syndrome induced by glucocorticoid. Methods A patient with iatrogenic Cushing's syndrome and diabetes mellitus was treated with oral dexamethasone tablets for 10 years. Results and conclusion the patients gradually reduced to the discontinuation of dexamethasone tablets and were replaced with hydrocortisone acetate 20 mg,bid replacement therapy. There was no withdrawal reaction and rebound phenomenon in the course of drug reduction. The patients were discharged from the hospital after corresponding treatment for the associated diseases. Clinical pharmacists play an important role in improving the accuracy of drug use and help to avoid the occurrence of drug-induced adverse drug reactions and unnecessary economic burden.
【作者单位】： 首都医科大学附属北京朝阳医院药事部;南京大学医学院附属南京鼓楼医院药学部;
【分类号】：R977.1
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