液体注射剂拉曼无损筛查数据库的建立

发布时间：2019-05-17 05:05

【摘要】：目的:建立拉曼光谱快速无损筛查液体注射液和大输液的数据库。方法:对拉曼无损检测液体的方法制定规范化操作规程(SOP),对每个注射液品种建立拉曼模型,根据动态验证的结果调节每个品种的个体化阈值,最终形成数据库用于液体注射剂的快速无损筛查。结果:建立了114个拉曼液体注射剂品种的拉曼无损筛查数据库。结论:随着液体注射剂拉曼光谱的不断累积,数据库将进一步步完善,实现现场液体注射液和大输液的快速无损检测。
[Abstract]:Objective: to establish a database for rapid and nondestructive screening of liquid injection and infusion by Raman spectroscopy. Methods: the standard operating procedure for Raman nondestructive testing liquid was established. (SOP), established Raman model for each injection variety, and adjusted the individualized threshold of each injection variety according to the results of dynamic verification. Finally, a database was formed for rapid nondestructive screening of liquid injections. Results: the Raman nondestructive screening database of 114 Raman liquid injection varieties was established. Conclusion: with the accumulation of Raman spectra of liquid injection, the database will be improved step by step to realize the rapid nondestructive testing of liquid injection and infusion.
【作者单位】：中国食品药品检定研究院;北京维登科学仪器有限责任公司;
【分类号】：R927.1

【共引文献】