气道吸入中性粒细胞弹性蛋白酶抑制剂对颅脑损伤误吸致肺损伤大鼠炎性因子及免疫功能的影响
发布时间:2019-05-17 08:05
【摘要】:正颅脑损伤(Brain injury)患者咽反射消失,食物或口咽分泌物容易误吸进入肺内,导致急性吸入性肺损伤(Acute lung injury,ALI),处理不及时还可能出现急性呼吸窘迫综合征(ARDS),甚至造成患者死亡~([1])。目前颅脑损伤继发肺损伤发病机制尚不明确,可能与活化中性粒细胞(Polymorphonulear leukocyte,PMN)释放细胞因子与过度炎症反应密切相
[Abstract]:In patients with positive craniocerebral injury (Brain injury), pharyngeal reflex disappears, food or oral and pharyngeal secretions are easy to be sucked into the lung by mistake, resulting in acute inhaled lung injury (Acute lung injury,ALI). (ARDS), may also appear in patients with acute respiratory distress syndrome (ARDS) if it is not treated in time. It even causes the death of the patient ~ ([1]). At present, the pathogenesis of lung injury secondary to craniocerebral injury is not clear, which may be closely related to the release of cytokines from activated neutrophils (Polymorphonulear leukocyte,PMN) and excessive inflammatory reaction.
【作者单位】: 安徽中医药大学;遵义医学院第一附属医院;安徽医科大学;
【分类号】:R965
本文编号:2478931
[Abstract]:In patients with positive craniocerebral injury (Brain injury), pharyngeal reflex disappears, food or oral and pharyngeal secretions are easy to be sucked into the lung by mistake, resulting in acute inhaled lung injury (Acute lung injury,ALI). (ARDS), may also appear in patients with acute respiratory distress syndrome (ARDS) if it is not treated in time. It even causes the death of the patient ~ ([1]). At present, the pathogenesis of lung injury secondary to craniocerebral injury is not clear, which may be closely related to the release of cytokines from activated neutrophils (Polymorphonulear leukocyte,PMN) and excessive inflammatory reaction.
【作者单位】: 安徽中医药大学;遵义医学院第一附属医院;安徽医科大学;
【分类号】:R965
【相似文献】
相关期刊论文 前7条
1 李建锋;王树凯;周辉;党博;;二甲基亚砜对大鼠颅脑损伤后Survivin基因表达的影响[J];中国实用神经疾病杂志;2008年04期
2 张晓华;葛建伟;陆兆丰;邱永明;罗其中;江基尧;;马来酸桂哌齐特对大鼠颅脑损伤作用效果的实验研究[J];医学信息(手术学分册);2007年07期
3 刘强;;氯胺酮对颅脑损伤神经细胞凋亡的影响[J];中国社区医师(医学专业);2011年29期
4 刘强;;氯胺酮对颅脑损伤神经细胞凋亡SOD、MDA的影响[J];中国医药指南;2011年16期
5 陈慧慧;王永青;彭余江;邵波;朱良才;段红宇;何玺君;李慧勇;杨鹏翔;杨帆;;吡格列酮对大鼠颅脑损伤后核转录因子、肿瘤坏死因子-α和细胞凋亡的影响[J];现代实用医学;2014年06期
6 金卫篷;王彬;赵子龙;尉辉杰;张永强;张建宁;;阿托伐他汀对颅脑损伤大鼠内皮祖细胞和神经功能的影响[J];天津医药;2013年05期
7 ;[J];;年期
,本文编号:2478931
本文链接:https://www.wllwen.com/yixuelunwen/yiyaoxuelunwen/2478931.html
最近更新
教材专著