抗菌药物限定日剂量对合理使用的影响分析

发布时间：2019-08-08 21:16

【摘要】：目的分析门诊抗菌药物的使用,为合理使用抗菌药物提供参考依据。方法随机选取2011-2013年门诊共计3 600张处方,以限定日剂量(DDD)为单位,分别计算3个年度抗菌药物的销售比例、使用强度、用药频度(DDDs)及每种药品的日治疗费用,对抗菌药物使用的合理性进行回顾性分析,数据采用SPSS 15.0软件进行统计分析。结果 3个年度中抗菌药物采购金额逐年增长,销售金额居于前3位的分别是头孢菌素类535.27万元、喹诺酮类401.56万元及青霉素类311.36万元;3个年度的抗菌药物使用强度排名前3位的分别是:头孢呋辛钠、头孢噻肟和左氧氟沙星;3个年度内抗菌药物DDDs排序位于前2名的均为头孢菌素类和喹诺酮类。结论抗菌药物应用基本合理,但仍有少数品种抗菌药物存在过量使用、联合用药率高,应加强抗菌药物监管,以推进抗菌药物的合理使用。
[Abstract]:Objective to analyze the use of antibiotics in outpatient department and to provide reference for rational use of antibiotics. Methods A total of 3600 prescriptions were randomly selected from outpatients from 2011 to 2013. According to the limited daily dose of (DDD), the sales ratio, intensity, frequency of (DDDs) and the daily treatment cost of each drug were calculated for three years, and the rationality of the use of antibiotics was analyzed retrospectively. the data were statistically analyzed by SPSS 15.0 software. Results the purchase amount of antibiotics increased year by year in the three years, and the top three sales amounts were cephalosporins 5.3527 million yuan, quinolones 4.0156 million yuan and penicillin 3.1136 million yuan respectively, and the top three antibiotics were cefuroxime sodium, cefotaxime and levofloxacin, respectively. In the first two years, cephalosporins and quinolones were the top two antimicrobial agents in the DDDs order of cephalosporins and quinolones. Conclusion the application of antibiotics is basically reasonable, but there are still a few varieties of antibiotics that are overused and the rate of combined use is high. The supervision of antibiotics should be strengthened in order to promote the rational use of antibiotics.
【作者单位】：莱芜市妇幼保健院药剂科;莱芜市妇幼保健院临床药学室;
【基金】：山东省卫生厅科研基金资助项目[莱科鉴字(2009)56]
【分类号】：R969.3

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