放射性药品生产人员内照射剂量估算方法探讨

发布时间：2018-01-18 11:00

本文关键词：放射性药品生产人员内照射剂量估算方法探讨　出处：《中国职业医学》2015年05期 　论文类型：期刊论文

【摘要】：目的探讨放射性药品生产人员内照射剂量估算方法。方法以某生产碘-125(125I)密封籽源和碘-131(131I)胶囊的密封企业为例,通过估算工作人员的摄入量,分析工作人员吸入放射性核素产生的内照射年受照剂量。结果生产125I密封籽源和131I胶囊的工作人员因吸入放射性核素造成的内照射年受照剂量为1.90 m Sv。与该企业的监测结果比较,125I工作场所的气溶胶放射性核素水平和工作人员的甲状腺剂量监测值分别与估算结果基本一致。结论放射性药品生产企业工作人员的内照射剂量不容忽视,应采取必要的辐射防护措施,设计合理的气流组织,定期对气溶胶进行有效监测。
[Abstract]:Objective to study the method of dose estimation for internal irradiation of radioactive drug manufacturers. Methods A sealed seed source and a capsule of iodine-131n 131I were used as an example for the production of iodine-125 and 125i. By estimating staff intake. Annual exposure doses of internal radiation from inhalation of radionuclides by workers were analysed. Results the annual exposure dose of 125i sealed seed sources and 131I capsules for workers who inhaled radionuclides was 1. .90. M Sv. compared with the monitoring results of the enterprise. The aerosol radionuclide level in 125I workplace and the thyroid dose monitoring values of the workers were basically consistent with the estimated results. Conclusion the internal radiation dose of the workers in the radioactive drug manufacturing enterprises should not be ignored. . Necessary radiation protection measures should be taken, reasonable airflow organization should be designed and aerosol should be monitored effectively on a regular basis.
【作者单位】：环境保护部核与辐射安全中心;
【分类号】：R144
【正文快照】： 放射性药品作为一种特殊类药品,以其灵敏性、早期性、动态直观性和无创伤性等特点,被广泛应用于核医学诊断和治疗方面。利用放射性药品进行显像,可从细胞水平进入到分子水平揭示活体内的组织结构和病理变化,在鉴别肿瘤良恶性和组织变性疾病方面具有极高的准确性;同时,放射性药

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