双酚A对记忆功能的影响及其机制研究进展

发布时间：2018-03-21 12:43

  本文选题：双酚A　切入点：记忆功能　出处：《现代预防医学》2017年16期 　论文类型：期刊论文

【摘要】：双酚A通过塑料食品包装材料迁移到食品中,从而被人体吸收,其可诱发多种疾病,对人体健康产生危害。该食品安全问题已引起国内外广泛关注,诸多研究表明双酚A可诱发肿瘤、影响生育等疾病,近年来又发现双酚A对记忆能力也有较大负面影响。本文从信号通路、突触可塑性与结构修饰、表观遗传修饰的改变等方面阐述双酚A对动物海马区记忆功能的影响及其机制方面的研究进行综述,以引起广大相关研究者的重视,并为食品安全防范提供科学依据。
[Abstract]:Bisphenol A (BPA) is absorbed by the human body through the migration of plastic food packaging materials, which can induce many diseases and harm human health. This food safety problem has aroused widespread concern at home and abroad. Many studies have shown that bisphenol A can induce tumors, affect fertility and other diseases. In recent years, it has been found that bisphenol A also has a negative effect on memory. The effects of bisphenol A on the memory function of hippocampal area of animals and its mechanism were reviewed in order to attract the attention of relevant researchers and provide scientific basis for food safety prevention.
【作者单位】： 哈尔滨医科大学药学院药物化学与天然药物化学教研室;
【基金】：黑龙江省大学生创新项目基金[项目编号201610226069] 哈尔滨市应用技术研究与开发项目基金[项目编号2016RAQXJ184]
【分类号】：R114
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本文编号：1643903