2009-2015年广东省云浮市手足口病流行病学特征和重症病例的病原学分析

发布时间：2018-03-24 12:54

本文选题：手足口病　切入点：流行特征　出处：《现代预防医学》2017年03期

【摘要】：目的探讨云浮市手足口病的流行病学及病原学特征,为防控手足口病提供科学依据。方法对2009-2015年云浮市报告的手足口病流行病学特征进行分析,结合重症病例个案流行病学调查,采用RT-PCR-荧光探针法检测患者粪便或肛拭子标本的肠道病毒类型(EV71、CA16和其他肠道病毒)。结果 2009-2015年云浮市共报告手足口病59 945例,年均发病率356.54/10万,居法定传染病首位,其中重症66例,死亡8例,发病呈夏季高峰和秋季次高峰的双峰分布,5岁以下儿童占87.82%(52 644/59 945),男女性别比1.69∶1,散居儿童占90.64%(54 335/59 945)。重症发生率110.10/10万,发生在5-7月的夏季高峰的占69.70%(46/66),0~2岁组占84.85%(56/66),重症病例中散居儿童占88.88%(58/66),但幼托儿童发生率(288.08/10万)大于散居儿童(106.75/10万)。重症病例中EV71病毒占80.00%(32/40)。8例死亡病例有6例为EV71病毒感染。结论云浮市手足口病在全市广泛流行,是一种危害儿童健康的高发常见病。当前应建立手足口病病原学的哨点监测系统,重点在5-7月的重症高发季节关注2岁以下儿童,加强EV71病原学监测。
[Abstract]:Objective to investigate the epidemiological and etiological characteristics of hand, foot and mouth disease in Yunfu City, and to provide a scientific basis for the prevention and control of hand foot and mouth disease. Methods the epidemiological characteristics of hand foot and mouth disease reported from 2009 to 2015 in Yunfu City were analyzed. Combined with epidemiological investigation of severe cases, a total of 59945 cases of hand, foot and mouth diseases were reported in Yunfu City from 2009 to 2015 by RT-PCR- fluorescence probe method for detection of enterovirus types of EV71, CA16 and other enterovirus in stool or anal swabs. The average annual incidence rate is 356.54 / 100, 000, ranking first among legal infectious diseases, including 66 severe cases and 8 deaths. The incidence rate of children under 5 years old was 87.82%, 52,644% 59,945%, the ratio of male to female was 1.69: 1, and the proportion of scattered children was 90.64% 54,335% 59,945%. The incidence of severe disease was 110.10% / 100 000. The summer peak in May-July was 69.70% in the age group of 84.85% and 56% in the 2-year-old group. In severe cases, the children living in the diaspora accounted for 88.88% of 66%, but the incidence rate of young children was 288.08% -100 000) more than that of the scattered children (106.75% -100 000). In severe cases, the proportion of EV71 virus accounted for 80.005% 32 / 40.8 cases of death. 6 cases were EV71 virus virus. Conclusion hand, foot and mouth disease is prevalent in Yunfu city. The sentinel surveillance system of hand-foot-mouth disease etiology should be established at present, with emphasis on children under 2 years of age in the severe high incidence season from May to July, and to strengthen the surveillance of EV71 etiology.
【作者单位】：云浮市疾病预防控制中心;
【分类号】：R725.1;R181.3

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