荞麦粉对高脂膳食大鼠脂代谢的影响

发布时间：2018-04-03 11:49

本文选题：荞麦粉　切入点：高脂膳食　出处：《现代食品科技》2015年06期

【摘要】：本文研究了荞麦粉(buckwheat,BW)对高脂膳食大鼠脂代谢的影响。将50只成年Wistar雄性大鼠随机分为基础对照组、高脂模型组、荞麦粉低、中、高剂量组(1、5、10 g/kg·d),每天喂食一次,饲喂30 d后腹主动脉取血,取出肝脏、肾周及睾丸附近脂肪,分别测定血清和肝脏中的总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)和低密度脂蛋白胆固醇(LDL-C)的水平,并观察肝脏病理切片。结果表明,与高脂膳食组相比,荞麦剂量组大鼠体重和食物摄入量都明显减少,肝重和脂肪重及其指数也明显降低,血清和肝脏中TC、TG、LDL-C的浓度降低,HDL-C的浓度升高。肝脏光镜结构表明,荞麦剂量组的肝脏脂肪变性均减轻,其中荞麦粉高剂量作用最为明显。说明荞麦粉干预高脂膳食,可起到降血脂、改善肝脏脂代谢、保护肝脏的作用,同时能够减少相关疾病的发生。
[Abstract]:The effect of buckwheat buckwheat (BW) on lipid metabolism in rats with high fat diet was studied.Fifty adult Wistar male rats were randomly divided into basic control group, hyperlipidemia model group, low buckwheat flour group, medium and high dose groups, fed once a day for 10 g/kg / d, fed with abdominal aorta for 30 days, and liver, perirenal and testicular fat were taken out.The serum and liver levels of TC, TG, HDL-C and LDL-C were measured, and the liver sections were observed.The results showed that compared with the high-fat diet group, the body weight and food intake of the buckwheat group were significantly decreased, the liver weight, fat weight and its index were also significantly decreased, and the serum and liver TGG LDL-C concentration decreased and HDL-C concentration increased.The structure of liver light microscope showed that the steatosis of liver was alleviated in the buckwheat dosage group, and the effect of high dose buckwheat powder was the most obvious.The results showed that buckwheat powder could reduce blood lipid, improve liver lipid metabolism, protect liver and reduce the incidence of related diseases.
【作者单位】：吉林医药学院公共卫生学院;吉林省中医药管理局二级实验室;
【基金】：吉林省科技发展计划基金(201105089)
【分类号】：R151;TS210.1

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