2011-2015年河北省手足口病流行特征及病原特征分析

发布时间：2018-04-10 19:50

  本文选题：手足口病 + 聚类分析　； 参考：《中华疾病控制杂志》2017年02期

【摘要】：目的分析河北省手足口病(hand foot and mouth disease,HFMD)的流行特征及病原学构成,为手足口病的防控提供科学依据。方法利用描述流行病学方法对河北省2011-2015年疾病监测信息报告系统上报的手足口病病例和实验室检测结果进行统计分析。结果 2011-2015年累计报告手足口病病例349 113例,年均发病率为95.91/10万,其中2012年和2014年报告发病率最高,呈现隔年高水平流行的现象。高发期集中在5~7月,10~12月间又出现一个次高峰或"拖尾"峰,患者主要为≤5岁儿童,尤其以1~3岁组婴幼儿为主。各地区发病水平存在差异,以发病率和重症率为分类指标对各地市进行聚类分析和赋值评价,得到重点防控地区为廊坊市、沧州市、衡水市、石家庄市、保定市和承德市。不同年份病原构成亦不同,在2013年和2015年其他肠道病毒分别取代柯萨奇病毒A组16型(coxsachievirus A16,Cox A16)、肠道病毒71型(enterovirus 71,EV71)成为当年主要病原体,构成比高达44.89%和66.23%。结论河北省手足口病呈现明显的季节、人群以及一定的地区分布规律,应进一步关注手足口病病原谱的变化,加强重点地区防控。
[Abstract]:Objective to analyze the epidemic characteristics and etiological composition of hand, foot and mouth disease (HFMD) of hand, foot and mouth disease (foot and mouth) in Hebei Province, so as to provide scientific basis for the prevention and control of hand, foot and mouth disease.Methods descriptive epidemiology was used to analyze the HFMD cases and laboratory results reported by the disease surveillance information system from 2011 to 2015 in Hebei province.Results A total of 349,113 HFMD cases were reported in 2011-2015, with an average annual incidence of 95.91 / 100000, among which the highest incidence was reported in 2012 and 2014.The period of high incidence was from May to July, from October to December, there was a sub-peak or "tail dragging" peak. The patients were mainly children 鈮，

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