日照市生活饮用水与富碘食品中碘的调查及补碘现状分析

发布时间：2018-05-15 18:27

本文选题：日照市 + 碘缺乏地区　；参考：《山东大学》2013年硕士论文

【摘要】：[目的] 针对当前补碘思路重在贯彻“科学补碘”的防治策略,调查日照市居民碘营养水平,为科学补碘与防治碘缺乏病提供基础资料与科学依据。 [方法] 在日照市所辖区域范围内,对居民生活饮用水水碘水平、对居民饮食有着重要影响的富碘食品的含碘量水平、8-10岁儿童尿碘水平、患甲状腺疾病的病例组及对照组尿碘水平、居民食用碘盐状况等进行调查分析。 [结果] 1.该研究在GB/T5750.5-2006生活饮用水中碘化物的硫酸铈催化分光光度法的基础上,建立了测定生活饮用水中微量碘的测定方法,该方法与GB/T5750.5-2006生活饮用水中碘化物的硫酸铈催化分光光度法比较,有着操作简单、在试验过程中易于控制等优点,能够适用于碘缺乏地区开展生活饮用水中碘的调查中大批量水样的测定。 2.该调查在日照市范围内共收集水样数据3369份,总体上水碘中位数为4.1μg/L,所辖区县水碘中位数分别为：东港区,4.0-g/L；岚山区,6.6μg/L；五莲县,4.21μg/L；莒县,3.2μg/L。其水碘频数分布经统计学检验,差异有统计学意义(x2=77.96,p0.01)。日照市辖区内的所有乡镇的水碘中位数均小于10μg/L,其频数分布也有差异,其中东港区三庄镇,莒县龙山、陵阳、桑园、库山、东莞等乡镇水碘中位数为1μg/L,沿海乡镇与内陆乡镇比较,其水碘中位数分别为6.6μg/L与3.8μg/L；其水碘分布差异具有统计学意义(x2=69.41,p0.01)。 3.针对市售富碘食品含碘量的差异,将富碘食品划分为高碘食品和其他富碘食品,建立富碘食品含碘量的测定方法。采用容量分析方法测定高碘食品的含碘量；利用碘催化砷铈氧化还原法测定含碘量相对较低的食品中的含碘量。通过富碘试样的合理分类,消除了含碘样品测定时取样的盲目性,在一定程度上克服了试样处理液在前处理过程中经反复稀释造成的误差。在含碘食品测定中采用适当的分析方法,重复测定6次不同含碘量的试样,其相对标准偏差在2.60%-9.52%。 4.对富碘食品含碘量进行检测分析,给出不同富碘含碘量的参考值。鲜蛤、鲜蛏、鲜海虹、虾皮、虾米中的含碘量较低,其平均值均不超过2mg/kg;湿海带、成品即食海带、干裙带菜、紫菜中含碘量平均值在19.6～118.0mg/kg,以干裙带菜含碘量较高；干海带是碘的良好来源,其含碘量在164～3256mg/kg,平均值为1050.8mg/kg。5.该调查共收集8-10岁儿童即时尿样476份,8-10岁儿童尿碘中位数为150.6μg/L；在患有甲状腺疾病的病例组与对照组尿碘水平调查中,病例组尿碘中位数略高于对照组,而两组尿碘频数分布差异无统计学意义(x2=5.92,p0.05)；共收集食用盐样品1322份,其碘盐合格率96.9%、合格碘盐食用率为95.9%、非碘盐率1.1%、碘盐覆盖率98.9%。 [结论] 1.该研究建立的测定生活饮用水中微量碘的测定方法,具有操作简单、试验过程易于控制等优点,适用于碘缺乏地区开展生活饮用水中碘的调查中大批量水样的测定。通过生活饮用水中碘含量的调查确定了日照市饮用水中水碘的分布特点,得出了日照市沿海乡镇居民饮用水水碘中位数比内陆乡镇略高的结论,为开展碘缺乏病的防治和饮用水水源的选择提供了理论依据。 2.针对市售富碘食品含碘量的差异,将富碘食品划分为高碘食品和其他富碘食品,建立富碘食品含碘量的测定方法。对日照市部分富碘食品含碘量进行检测分析,给出不同富碘含碘量的参考值。不同食品中含碘量差异较大,不同富碘食品中含碘量也有较大差异,不同产地的同一富碘食品其含碘量也存在较大的差异,同一产品的不同的取样位置含碘量也有所不同。 3.日照市属碘缺乏地区,日照市生活饮用水水碘的分布不均衡；食物中的碘含量差异较大,仅从饮食角度补碘难以满足机体需要；实施补碘措施后,人群碘营养水平达到充足且稍偏高状态,随着人们对科学补碘意识的提高,碘营养水平更趋向合理。
[Abstract]:Purpose of the project

According to the current idea of iodine supplementation , the iodine nutrition level of residents in Rizhao City is investigated and the basic information and scientific basis for scientific iodine supplementation and iodine deficiency prevention are provided .

Methodology

In the area of Rizhao city , the iodine level of drinking water in drinking water was studied , the iodine content of iodine - rich food with important influence on residents ' diet , the urinary iodine level of children aged 8 - 10 years , the level of urinary iodine in children with thyroid diseases and the iodine level in the control group were investigated and analyzed .

The result is not valid .

1 . The determination method of trace iodine in drinking water is established based on the cerium sulfate catalytic spectrophotometric method of iodide in drinking water of GB / T 5750 . 5 - 2006 . The method has the advantages of simple operation , easy control during testing and the like , and can be applied to the determination of large batch of water samples in the investigation of iodine deficiency in living drinking water in iodine deficiency area .

2 . The survey collected 3369 samples of water samples in Rizhao City , the median of total water iodine was 4.1 渭g / L , and the median water iodine number in the districts was 4 . 0 - g / L .
Lanshan region , 6.6渭g / L ;
Wulian county , 4.21渭g / L ;
There was statistical significance ( x2 = 77.96 , p0.01 ) in the distribution of iodine frequency in Juxian County , 3.2 渭g / L . The median number of water iodine in all villages and towns in Rizhao City is less than 10渭g / L , and its frequency distribution is different . Among them , the median of iodine in villages and towns in Donggang Town , Longshan , Lingyang , Sanyuan , Kuyama , Dongguan and other towns is 1 渭g / L , and the median number of water iodine in coastal towns and towns is 6.6 渭g / L and 3.8 渭g / L , respectively .
The difference of water iodine distribution was significant ( x2 = 69.41 , p0.01 ) .

3 . According to the difference of iodine content in iodine - enriched food , iodine - enriched food was divided into high - iodine food and other iodine - rich foods , and the method for measuring iodine content in iodine - enriched food was established . The iodine content of high - iodine food was determined by volumetric analysis method .
The iodine content in foods with relatively low iodine content was determined by the method of iodine - catalyzed arsenic - cerium oxide reduction . By reasonable classification of iodine - rich samples , the blindness of sampling during the determination of iodine - containing samples was eliminated , and the errors caused by repeated dilution in the pretreatment process were overcome . The relative standard deviation was 2.60 % - 9.52 % .

4 . The iodine content of iodine - enriched food was analyzed and the reference value of iodine content of different iodine - rich foods was given . The iodine content of fresh clam , fresh razor clam , fresh sea rainbow , shrimp skin and shrimp was lower than 2mg / kg ; the average value of iodine content in wet kelp , finished product instant kelp , dried undaria and Thallus Porphyrae was 19.6 - 118.0 mg / kg , with higher iodine content in dried undaria .
Dry kelp is a good source of iodine . Its iodine content is 164 ~ 3256mg / kg , the average value is 101.8mg / kg . 5 . The survey collected 476 samples of children aged 8 - 10 years . The median of urinary iodine in children aged 8 - 10 years is 150.6 渭g / L .
In the case group with thyroid disease and the control group , the median urinary iodine number was slightly higher than that in the control group , while there was no significant difference between the two groups ( x2 = 5.92 , p0.05 ) .
The qualified rate of iodized salt was 96.9 % , the rate of qualified iodized salt was 95.9 % , the rate of non - iodized salt was 1.1 % , and the rate of iodized salt was 98 . 9 % .

Conclusion

1 . The method of determination of trace iodine in drinking water is established by the research . It has the advantages of simple operation , easy control and so on . It is suitable for the determination of iodine in drinking water in drinking water in the area of iodine deficiency . By investigating the iodine content in drinking water , the conclusion that the median number of iodine in drinking water in drinking water in the coastal towns of Rizhao city is higher than that of the inland villages and towns is obtained , which provides the theoretical basis for the prevention and control of iodine deficiency disease and the choice of drinking water source .

2 . According to the difference of iodine content in iodine - rich foods , the iodine - rich food was divided into high - iodine food and other iodine - rich foods . The iodine content of iodine - rich foods in Rizhao city was analyzed . The iodine content of different iodine - rich foods was significantly different .

3 . Rizhao city belongs to iodine deficiency area , and the distribution of iodine in drinking water in Rizhao city is not balanced ;
the iodine content in the food is different , and only the iodine supplementation in the diet is difficult to meet the needs of the organism ;
After the iodine supplementation , the iodine nutrition level of the population is sufficient and slightly higher , and the iodine nutrition level is more reasonable with the improvement of scientific iodine supplementation awareness .

【学位授予单位】：山东大学
【学位级别】：硕士
【学位授予年份】：2013
【分类号】：R151

【参考文献】