新疆伊犁哈萨克族学龄儿童体质指数及血压与代谢指数的关系研究

发布时间：2018-09-02 07:41

【摘要】：目的：了解新疆伊犁地区7～14岁哈萨克族儿童超重、肥胖、血压水平和高血压的发生状况，比较分析体质指数(BMI)及血压与代谢指数的关系。方法：采用随机整群抽样方法,抽取新疆伊犁地区7～14岁哈萨克族学龄儿童2438例，进行身高、体重、腰围、臀围、皮褶厚度、血压测量，并计算BMI；分别检测28例肥胖高血压组、58例单纯性肥胖组及60例正常对照组儿童的代谢指数(总胆固醇TC、甘油三脂TG、高密度脂蛋白HDL、低密度脂蛋白LDL、空腹血糖FPG、空腹胰岛素FINS)，计算胰岛素抵抗指数(HOMA-IR)，并分析3组间各指标均数的差异，体质指数(BMI)、收缩压(SBP)及舒张压(DBP)与各指标的相关关系。结果：(1)新疆伊犁地区7～14岁哈萨克族儿童肥胖率为1.64%(40/2438)，超重率为5.13%(25/2438)；(2)儿童收缩压(SBP)平均水平(94±13)mmHg，，舒张压(DBP)平均水平为(60±9)mmHg；高血压患病率5.7%(138/2438)；(3)SBP、DBP及高血压患病率与性别、年龄、BMI、腰围、臀围、皮褶厚度均呈正相关。(4)3组间BMI、SBP、DBP、TC、TG、HDL、LDL、FPG、FINS、HOMA-IR的均数相比均差异显著(P0.05)，以肥胖高血压组儿童TC、LDL、FPG、HOMA-IR的均数值最大，肥胖高血压组儿童HDL的均数值最小。(5)Pearson相关法分析：BMI与TC、LDL、FPG、FINS、HOMA-IR有直接相关关系，与HDL不存在直接相关关系，与TG无相关关系；SBP、DBP与TC、HDL、LDL、FPG、FINS、HOMA-IR不存在直接相关关系，与TG无相关关系。(6)多重线性回归分析：以TC、TG、HDL、LDL、FPG、FINS、HOMA-IR为自变量，以BMI为因变量，TC、HDL、LDL、HOMA-IR进入方程；以SBP为因变量，TC、HDL、LDL，HOMA-IR进入方程；以DBP为因变量，TG、HDL、LDL，HMOA-IR进入方程。结论：与汉族儿童相比，哈萨克族儿童肥胖率介于中小城市与富裕乡村水平间；血压平均水平较国内儿童低，高血压患病率处于国内外同年龄段儿童的中等水平，肥胖与哈萨克族儿童高血压患病率密切相关；儿童肥胖及肥胖伴高血压的发生，与血脂紊乱、胰岛素抵抗指数关系密切，是否与血糖异常有关系需深入研究。血脂紊乱、血糖异常、胰岛素抵抗指数与血压的关系也需要近一步研究与探讨。
[Abstract]:Objective: to investigate the prevalence of overweight, obesity, blood pressure and hypertension among Kazakh children aged 7 ~ 14 years in Yili area, Xinjiang, and to compare the relationship between body mass index (BMI), blood pressure and metabolic index. Methods: 2438 Kazakh school-age children aged 7 or 14 years in Yili area of Xinjiang were selected by random cluster sampling. Height, weight, waist circumference, hip circumference, skinfold thickness, blood pressure were measured and BMI; was calculated. Metabolic index (total cholesterol, TC, triglyceride, TG, high density lipoprotein, HDL, low density lipoprotein, LDL, fasting insulin) in 58 simple obese children and 60 normal controls were measured. The insulin resistance index (HOMA-IR) was calculated by FINS), and the differences of the mean values of each index among the three groups were analyzed. Body mass index (BMI),) systolic blood pressure (SBP) and diastolic blood pressure (DBP) were correlated with each index. Results: (1) the obesity rate was 1.64% (40 / 2438) and overweight rate was 5.13% (25 / 2438); (/ 2) among Kazak children aged 714 years in Yili, Xinjiang. The mean (SBP) level of systolic blood pressure (SBP) was (94 卤13) mmHg, diastolic blood pressure (DBP) was (60 卤9) mmHg; and the prevalence of SBP,DBP, hypertension and sex was (60 卤9) mmHg;. Age, waist circumference, hip circumference and skinfold thickness were positively correlated. (4) the mean number of BMI,SBP,DBP,TC,TG,HDL,LDL,FPG,FINS,HOMA-IR was significantly different among the three groups (P0.05). The average value of HDL was the lowest in obese hypertensive children. (5) Pearson correlation analysis showed that there was a direct correlation between HDL and HDL, but no direct correlation with HDL, and there was no direct correlation between Pearson and TC,HDL,LDL,FPG,FINS,HOMA-IR. (6) multiple linear regression analysis: using TC,TG,HDL,LDL,FPG,FINS,HOMA-IR as independent variable, BMI as dependent variable, SBP as dependent variable, and DBP as dependent variable. Conclusion: compared with Han children, the obesity rate of Kazak children is between the middle and small cities and the rich rural areas, the average blood pressure is lower than that of the domestic children, and the prevalence of hypertension is at the middle level of the same age children at home and abroad. Obesity is closely related to the prevalence of hypertension in Kazakh children, and the occurrence of obesity with hypertension in children is closely related to dyslipidemia and insulin resistance index, and whether there is a relationship between obesity and abnormal blood glucose needs further study. The relationship between hyperlipidemia, abnormal blood glucose, insulin resistance index and blood pressure also needs further study and discussion.
【学位授予单位】：新疆医科大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R179

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