陕西省关中地区健康人群脑膜炎奈瑟菌带菌状况调查与分析

发布时间：2018-10-19 18:41

【摘要】：目的了解陕西省关中地区健康人群脑膜炎奈瑟菌(Neisseria meningitidis,Nm)的带菌状况,为流行性脑脊髓膜炎(流脑)防治提供依据。方法在西安市和宝鸡市共选择998名健康人群采集咽拭子进行细菌分离培养和PCR核酸检测,并将阳性Nm株进行分群。结果关中地区健康人群Nm总带菌率为6.42%(64/998)。宝鸡市人群Nm带菌率(8.25%)显著高于西安市(4.50%)(χ~2=5.85,P0.05)。15-24岁年龄组带菌率(13.45%)显著高于0-2岁年龄组(4.71%)(χ~2=7.89,P0.05)。在64株Nm阳性菌株中,A、B、C和不可分群分别占1.56%、7.81%、25.00%和65.63%。结论关中地区健康人群Nm带菌率总体较低,菌群分布与中国其他地区基本一致。
[Abstract]:Objective to investigate the bacterial status of Neisseria meningitidis (Neisseria meningitidis,Nm) in Guanzhong area of Shaanxi Province and to provide evidence for prevention and treatment of epidemic meningitis (meningitis). Methods A total of 998 healthy people were collected from Xi'an and Baoji cities for bacterial isolation, culture and PCR nucleic acid detection, and the positive Nm strains were divided into groups. Results the total carrying rate of Nm was 6.42% (64 / 998) in the healthy population in Guanzhong area. The rate of Nm carrying in Baoji population (8.25%) was significantly higher than that in Xi'an city (4.50%) (蠂 ~ 2 5.85%, P0.05). The rate of carrying bacteria in 15-24 age group (13.45%) was significantly higher than that in 0-2 age group (4.71%) (蠂 ~ 2 + 7.89 P 0.05). Among the 64 Nm positive strains, the percentage of Nm positive strains was 1.567.81% and 65.6333%, respectively. Conclusion the Nm carrier rate of healthy population in Guanzhong area is lower, and the distribution of bacterial flora is consistent with that of other regions in China.
【作者单位】：陕西省疾病预防控制中心;宝鸡市疾病预防控制中心;西安市疾病预防控制中心;
【分类号】：R181.3;R515.2

【相似文献】