全谷物调节代谢性疾病机制研究的新视角——肠道微生物

发布时间：2018-11-07 21:09

【摘要】：全谷物中含有丰富的植物化学素和多种营养成分,增加全谷物的摄入能够显著降低代谢性疾病(如肥胖、Ⅱ型糖尿病)的发生率,然而也正是由于全谷物成分复杂,很多现有的体外研究模型和方法并不适用于全谷物保健机制的研究。随着肠道微生物与人体健康之间的关系逐步得到揭示,肠道微生物启发了全谷物健康保健机制的研究方向。本文将详细介绍肠道微生物与代谢性疾病、全谷物成分与肠道微生物以及全谷物与肠道微生物之间的研究现状,并分析以肠道微生物作为全谷物保健机制研究靶点的可行性,目的在于为明确健康作用的全谷物及其相关产品的综合开发提供研究思路,使得来源广泛、食用方便、功效显著的全谷物更好地服务于人类健康。
[Abstract]:Whole grains are rich in phytochemicals and a variety of nutrients. Increasing the intake of whole grains can significantly reduce the incidence of metabolic diseases, such as obesity, type 2 diabetes, but also because of the complex composition of whole grains. Many existing in vitro research models and methods are not suitable for the study of whole grain health mechanism. As the relationship between intestinal microbes and human health has been gradually revealed, intestinal microbes have inspired the research direction of whole grain health care mechanism. This paper will introduce the research status of intestinal microorganism and metabolic disease, whole grain composition and intestinal microorganism, and analyze the feasibility of using intestinal microorganism as the target of whole grain health care mechanism. The purpose of this study is to provide a research idea for the comprehensive development of whole grain and its related products, so that the whole grain, which has a wide range of sources, is convenient to eat and has remarkable effect, can serve human health better.
【作者单位】：北京工商大学北京食品营养与人类健康高精尖创新中心食品添加剂与配料北京高校工程研究中心;
【基金】：国家自然科学基金项目(31501480,31571940,31271976)
【分类号】：R151

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