某社区0~3岁儿童体重与6种指血无机元素含量调查分析

发布时间：2019-01-28 12:29

【摘要】：目的本研究旨在了解武昌区某社区0～3岁健康儿童的体重、6种指血无机元素（锌、铁、钙、镁、铜和铅）含量，探讨并评价该地区儿童体重与6种指血无机元素的关系，为该地区儿童保健工作提供参考依据，并为今后开展有效的干预措施提供依据。对象2009年10月到2011年4月期间在武昌区某社区医院儿保科做健康体检的0～36月龄644名健康儿童（剔除患有佝偻病、感染、贫血、腹泻等疾病的儿童），其中男性369名，女性275名，平均年龄10.8月龄。方法体重评价采用WHO0~18岁儿童生长发育参考标准。体重测量按第七版《实用儿科学》体检方法进行，精确到0.01kg。超重和肥胖的判断根据同年龄、同性别身高-体重法判断。6种指血无机元素由专业的检验员采集左手环指末梢血，使用的是MP-2型溶出分析仪(A型)（山东生产）溶出电位法，可检测出血清铁、锌、钙、镁、铜、铅。逐一登记，将数据编制成表格，统一运用Excel建立数据库，并采用SPSS17.0软件，进行T检验、卡方检验、协方差分析和相关检验。结果该社区0～36月龄儿童体重水平整体高于2006年WHO新标准参考值均值水平，处于中等及以上水平。超重肥胖检出率分别为20.7%和8.1%，超重-肥胖比为2.5，，各年龄段中以0～6月龄组儿童超重肥胖率最高（超重率27.5%,肥胖率12.7%），男童超重肥胖率高于女童（男童：33.1%，女童：22.5%）。肥胖超重检出率存在性别、年龄差异。儿童6种指血无机元素含量在各年龄段存在性别差异：0～6月龄，男童血铅含量明显大于女童（t=10.465,P=0.001），7～12月龄组女童血钙含量显著大于男童（t=5.749,P=0.017），13～36月龄男童血铜、血铅含量明显高于女童（t=10.306,P=0.002）。儿童以缺钙（29.3%）为最高，其次依次是缺锌（17.4%）、缺镁（13.5%）、缺铁（5.1%），该社区儿童中无血铜缺乏者，高血铅率为5.9%。血铁缺乏存在显著年龄差异（ⅹ~2=6.472，P=0.039）。男女儿童血中都含有铅元素，但男童的高铅率明显高于女童（ⅹ~2=4.432，P=0.035）。0～36月龄儿童血锌、铁元素联合缺乏率达6.6%，其中在0～6月龄组最常见，其后随年龄增长而降低。6种无机元素相关性分析显示：除血锌与铜、血钙与铜无显著相关外，血锌、血铁、血钙、血镁、血铜5种无机元素均存在显著相关（P＜0.01）。7～12月龄组儿童血锌、铁、钙缺乏组和正常对照组的体重及WAZ均存在差异（P＜0.05）。13～36月龄组男童血锌缺乏组与正常对照组的WAZ存在差异（t=2.538,P=0.013）。0～6月龄组和7～12月龄组男童高血铅组与正常对照组儿童体重存在差异（t=-2.247,P=0.026）。结论该社区儿童肥胖超重情况较为突出，有其是男童。该社区儿童血锌、血铁、血钙、血镁、血铜5种无机元素含量均处在正常范围的中等或中等以上水平，血铅含量低于全国儿童调查水平，高血铅率低于全国调查水平。血锌、血铁缺乏与儿童体重有关。
[Abstract]:Objective to investigate the body weight and the contents of inorganic elements (zinc, iron, calcium, magnesium, copper and lead) in children aged 3 years in a community in Wuchang District, and to explore and evaluate the relationship between the body weight of children and the inorganic elements of six finger blood in Wuchang District. It provides reference basis for children's health care in this area, and provides basis for effective intervention in the future. Participants from October 2009 to April 2011, 644 healthy children (excluding children with rickets, infection, anemia, diarrhoea and other diseases) were examined in the Department of Child Care in a community hospital in Wuchang District, including 369 males, and 644 healthy children aged 36 months (excluding children with rickets, infection, anemia, diarrhoea, etc.), There were 275 females with an average age of 10.8 months. Methods the body weight was evaluated by the reference standard of growth and development of children aged WHO0~18. The weight measurement was carried out according to the seventh edition of practical Pediatrics, and the accuracy was 0.01kg. The judgment of overweight and obesity was based on the same age, same sex height and weight. Six inorganic elements of finger blood were collected by professional examiners. MP-2 type dissolution analyzer (type A) (Shandong production) was used to detect serum iron, zinc, calcium, magnesium, copper and lead. Register the data one by one, compile the data into tables, establish the database by using Excel, and use SPSS17.0 software to carry out T test, chi-square test, covariance analysis and correlation test. Results the body weight level of 0 ~ 36 months old children in this community was higher than the average level of the new standard reference value of WHO in 2006, and it was in the middle level and above level. The prevalence rate of overweight and obesity was 20.7% and 8.1%, respectively, and the ratio of overweight to obesity was 2.5. The overweight and obesity rate was the highest in children of 0 to 6 months of age (27.5% and 12.7%). The rate of overweight and obesity in boys was higher than that in girls (33.1% for boys and 22.5% for girls). There were sex and age differences in the prevalence of obesity and overweight. The contents of inorganic elements in 6 finger blood of children were significantly higher than those of girls at 0 ~ 6 months of age (t = 10.465p ~ (0.001), and the contents of serum calcium in girls of 7 ~ 12 months old were significantly higher than those of boys (t = 5.749), while the contents of inorganic elements in children's blood were significantly higher than those in girls (t = 10.465p ~ (0.001). The levels of blood lead in boys aged 13 to 36 months were significantly higher than those in girls (t = 10.306, P < 0.002). Calcium deficiency (29.3%) was the highest in children, followed by zinc deficiency (17.4%), magnesium deficiency (13.5%) and iron deficiency (5.1%). There was significant age difference in blood iron deficiency (x ~ 2 + 6.472 P 0.039). Both boys and girls had lead elements in their blood, but the high lead rate of boys was significantly higher than that of girls (x ~ 2 ~ 4. 432P ~ 0. 035). The blood zinc and iron deficiency rates of children aged 36 months were 6. 6%, especially in 0 ~ 6 months old group. The correlation analysis of 6 inorganic elements showed that except blood zinc and copper, blood calcium and copper had no significant correlation, blood zinc, blood iron, blood calcium, blood magnesium, There were significant correlations among 5 inorganic elements in blood copper (P < 0.01). There was significant difference in body weight and WAZ between the calcium deficiency group and the normal control group (P < 0. 05), and the WAZ of the 13 ~ 36 month old boys with zinc deficiency was significantly different from that of the normal control group (t 2. 538). There was a significant difference in body weight between the boys with high blood lead and the normal control group (t = -2.247, P < 0. 026), and there was no significant difference in body weight between 0 and 12 months old boys (P < 0. 013). Conclusion the obesity and overweight rate of children in this community is more prominent, some of them are boys. The contents of serum zinc, iron, calcium, magnesium and copper in blood of children in this community were all in the medium or above normal range, the blood lead content was lower than the national investigation level, and the high blood lead rate was lower than the national investigation level. Blood zinc and iron deficiency are associated with children's weight.
【学位授予单位】：武汉科技大学
【学位级别】：硕士
【学位授予年份】：2012
【分类号】：R179

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