强化混合超临界辅助雾化法制备玉米醇溶蛋白微粒
发布时间：2018-11-11 12:59
【摘要】：玉米醇溶蛋白是一种具有强疏水性的天然植物蛋白,在食品和医药等行业具有良好的应用潜力。本文采用强化混合超临界流体辅助雾化技术(SAA-HCM)制备玉米醇溶蛋白超细微粒,研究相关实验参数如混合气压力与温度、沉淀器温度、玉米醇溶蛋白浓度及乙醇浓度等对微粒形貌、粒径的影响。实验结果表明在9.0 MPa的混合器压力,混合器温度和沉淀器温度分别为50℃和60℃,玉米醇溶蛋白浓度为20 g?L-1,乙醇浓度为80%条件下,制得的微粒具有球形度高、分散性好、粒径可控制等优点,且平均粒径约为3μm。此外,本文以醇溶蛋白为载体、VD3为模拟活性药物制备载药微粒,并对其形貌、载药率和药物释放行为做初步探索,取得了合理的包埋缓释效果。
[Abstract]:Zein is a natural plant protein with strong hydrophobicity and has good application potential in food and medicine industries. In this paper, Zein ultrafine particles were prepared by enhanced supercritical fluid assisted atomization (SAA-HCM). The experimental parameters such as mixture pressure and temperature, precipitator temperature were studied. The effects of concentration of Zein and ethanol on the morphology and particle size of the particles. The experimental results show that under the conditions of 9.0 MPa mixer pressure, mixer temperature and precipitator temperature of 50 鈩，
本文编号：2324908
[Abstract]:Zein is a natural plant protein with strong hydrophobicity and has good application potential in food and medicine industries. In this paper, Zein ultrafine particles were prepared by enhanced supercritical fluid assisted atomization (SAA-HCM). The experimental parameters such as mixture pressure and temperature, precipitator temperature were studied. The effects of concentration of Zein and ethanol on the morphology and particle size of the particles. The experimental results show that under the conditions of 9.0 MPa mixer pressure, mixer temperature and precipitator temperature of 50 鈩，
本文编号：2324908
本文链接：https://www.wllwen.com/shekelunwen/minzhuminquanlunwen/2324908.html
