血常规参数在重症疟疾中的诊断价值

发布时间：2017-12-27 07:40

本文关键词：血常规参数在重症疟疾中的诊断价值　出处：《南通大学学报(医学版)》2016年05期 　论文类型：期刊论文

【摘要】：目的:观察白细胞计数(white blood cell,WBC)、中性粒细胞比例(N%)、红细胞分布宽度(red cell distribution width,RDW)、血小板计数(platelet,PLT)、血小板分布宽度(platelet distribution width,PDW)等血常规常见参数在重症疟疾及普通疟疾患者中的变化,探讨其在重症疟疾中的诊断价值。方法:回顾性分析2008年7月—2014年6月我院收治的疟疾患者的临床资料,按疾病危重程度分为重症疟疾组与普通疟疾组,记录两组患者的基本情况及入院时的血常规参数,比较两组参数的差异。结果:重症疟疾组与普通疟疾组相比,在急性生理学与慢性健康状况评分系统Ⅱ(acute physiology and chronic health evaluation scoring systemⅡ,APACHEⅡ评分)(17.67±7.63 vs 10.81±2.17,P0.01)、序贯器官衰竭(sequential organ failure assessment,SOFA)评分(8.50±5.92 vs 3.37±1.88,P0.01)、RDW(42[40.50,50.20]vs 41[38.00,44.00],P0.05)、PDW(17.95[15.95,19.88]vs14.60[12.80,17.00],P0.01)等方面差异有统计学意义;联合使用RDW与PDW时,曲线下面积略高于APACHEⅡ评分(0.836±0.055 vs 0.819±0.069,P0.05)及SOFA评分(0.836±0.055 vs 0.829±0.064,P0.05)。结论:PDW、PDW与疟疾危重度具有相关性,PDW联合RDW可有效鉴别重症疟疾,且在方便性与时效性上优于APACHEⅡ评分及SOFA评分。
[Abstract]:Objective: To observe the white blood cell count (white blood, cell, WBC), neutrophil percentage (N%), red cell distribution width (red cell distribution width, RDW), platelet count (platelet, PLT), platelet distribution width (platelet distribution width, PDW) changes of blood parameters in common and common malaria severe malaria in patients, to discuss its diagnostic value in severe malaria. Methods: the clinical data of malaria patients in our hospital from July 2008 to June 2014 were retrospectively analyzed. They were divided into severe malaria group and common malaria group according to the severity of the disease. The basic condition of two groups and routine blood parameters at admission were recorded, and the difference between the two groups was compared. Results: severe malaria group compared with normal group in malaria, and chronic health evaluation II acute physiology (acute physiology and chronic health evaluation scoring system II, APACHE II score (17.67) + 7.63 vs 10.81 + 2.17, P0.01), sequential organ failure (sequential organ failure assessment, SOFA (8.50 +) score 5.92 vs 3.37 + 1.88, P0.01), RDW (42[40.50,50.20]vs 41[38.00,44.00] P0.05), PDW (17.95[15.95,19.88]vs14.60[12.80,17.00], P0.01) had significant differences; the combined use of RDW and PDW, the AUC is slightly higher than the APACHE score (0.836 + 0.055 vs 0.819 + 0.069, P0.05) and SOFA score (0.836 + 0.055 vs 0.829 + 0.064, P0.05). Conclusion: PDW and PDW are correlated with malaria severity. PDW combined with RDW can effectively identify severe malaria, and is superior to APACHE II score and SOFA score in convenience and timeliness.
【作者单位】：江苏省南通市第三人民医院ICU;
【分类号】：R531.3
【正文快照】： 疟疾是迄今世界上最严重的热带虫媒传染病之一,其与艾滋病、结核病被公认为全球最严重的三大公共卫生问题,每年因感染疟疾而死亡的人数已经超过艾滋病。随着国际贸易、劳务输出、旅游等人员来往频繁,我省输入性恶性疟疾明显增加[1]。恶性疟疾是疟疾中较少见的一种,发热常不规

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