5%转化糖电解质注射液辅助治疗成人重症感染性腹泻的回顾性分析

发布时间：2018-01-14 08:40

本文关键词：5%转化糖电解质注射液辅助治疗成人重症感染性腹泻的回顾性分析　出处：《中国药房》2015年05期 　论文类型：期刊论文

【摘要】：目的:评价5%转化糖电解质注射液对成人重症感染性腹泻的能量及电解质补充以及纠正酸中毒的作用。方法:采用回顾性分析方法,根据用药情况分为对照组56例,用复方氯化钠注射液500 ml,ivgtt,qd;治疗组70例,用5%转化糖电解质注射液500 ml,ivgtt,qd。而两组患者其他抗感染、对症支持治疗相同。结果:两组患者低血钾、酸中毒在24 h(χ2=4.31,P0.05;χ2=5.20,P0.05)、48 h(χ2=4.83,P0.05;χ2=3.87,P0.05)、72 h(χ2=7.82,P0.01;χ2=6.81,P0.01)恢复率比较差异均有统计学意义;脱水纠正时间(t=1.78,P0.05)、症状缓解时间(t=2.24,P0.05)、整个病程(t=1.93,P0.05)比较差异也有统计学意义。结论:5%转化糖电解质注射液可及时纠正低血钾及酸中毒,及时补充能量,缓解症状,缩短病程。
[Abstract]:Objective: to evaluate the effect of 5% transforming sugar electrolyte injection on energy and electrolyte supplementation and acidosis correction in adult patients with severe infectious diarrhea. Methods: retrospective analysis was used. According to the drug situation, 56 cases were divided into control group and treated with compound sodium chloride injection 500 ml / d iv GTT QD. In the treatment group, 70 cases were treated with 5% ml of glucose electrolyte injection, iv gttt QD. The other anti-infection and symptomatic support therapy were the same in the two groups. Results: hypokalemia was found in the two groups. Acidosis was found in 24 hours (蠂 ~ 2 = 4.31) P 0.05; 蠂 ~ 2 ~ 2 ~ (5.20) P _ (0.05) ~ (48) h (蠂 ~ (2) ~ (2)) 4.83 (P ~ (0.05)); 蠂 ~ 2 ~ (2) ~ (3.87) (P _ (0.05)) ~ (72) h (蠂 ~ (2)) ~ (7.82) (P ~ (0.01)); There were significant differences in the recovery rate between the two groups. The time of dehydration correction was 1.78% P0.05, the time of symptom remission was 2.24% P0.05, and the whole course of disease was 1.93. Conclusion 5% sugar electrolyte injection can correct hypokalemia and acidosis in time, replenish energy, relieve symptoms and shorten the course of disease.
【作者单位】：河北联合大学附属医院感染性疾病科;解放军第255医院感染性疾病科;
【分类号】：R512.5
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