阿米替林联合普瑞巴林治疗72例带状疱疹后神经痛患者临床疗效观察

发布时间：2018-02-13 18:00

本文关键词： 阿米替林普瑞巴林带状疱疹后神经痛　出处：《世界最新医学信息文摘》2016年A0期 　论文类型：期刊论文

【摘要】：目的探讨盐酸阿米替林片与普瑞巴林胶囊联合治疗带状疱疹后神经痛患者临床疗效及生存质量的影响。方法选取本院2015年1月至2016年10月收治的带状疱疹后神经痛患者72例患者为研究对象,根据随机数字表将患者分为两组,治疗组给予盐酸阿米替林片与普瑞巴林胶囊联合治疗,观察组给予盐酸阿米替林片治疗,对比分析两组患者在疼痛减轻情况、生存质量改善情况、不良反应发生情况等方面的差异。结果治疗组开始治疗后第1、2、3周VAS评分均较观察组明显降低(P0.05),生存质量明显改善(P0.05),结果均有统计学意义;两组均有不良反应出现,但差异无统计学意义(P0.05)。结论盐酸阿米替林片联合普瑞巴林胶囊在减轻带状疱疹后神经痛、改善生存质量等方面具有显著疗效,安全性相对较高,值得临床上广泛推广。
[Abstract]:Objective to investigate the effect of amitriptyline hydrochloride combined with PreBahrain capsule on the treatment of postherpetic neuralgia and its quality of life (QOL). Methods from January 2015 to October 2016, the patients with postherpes zoster nerve were selected in our hospital. 72 patients with pain were studied. According to the random number table, the patients were divided into two groups. The treatment group was treated with amitriptyline hydrochloride tablets combined with PreBahrain capsule, and the observation group with amitriptyline hydrochloride tablets. The pain relief of the two groups was compared and analyzed. Results the VAS scores of the treatment group were significantly lower than those of the observation group at the 1st and 2nd week after treatment, and the quality of life was improved significantly (P 0.05). There were adverse reactions in both groups, but there was no significant difference between the two groups. Conclusion Amitriptyline hydrochloride combined with PreBahrain capsule has a significant effect on relieving postherpetic neuralgia and improving the quality of life, and the safety is relatively high. It is worth popularizing widely in clinic.
【作者单位】：青海省人民医院;
【分类号】：R752.12

【相似文献】