河南省2016年健康人群麻疹、风疹、流行性腮腺炎抗体水平监测
发布时间:2018-02-16 00:38
本文关键词: 麻疹 风疹 流行性腮腺炎 抗体水平 出处:《中国疫苗和免疫》2017年04期 论文类型:期刊论文
【摘要】:目的了解河南省2016年健康人群麻疹、风疹、流行性腮腺炎(流腮)抗体水平。方法采用系统抽样方法选择河南省3个县(区)8个年龄组共449名健康人采集血标本,用酶联免疫吸附试验(ELISA)测定血清中麻疹、风疹、流腮Ig G抗体。结果在449名监测对象中,麻疹、风疹、流腮抗体阳性率分别为93.99%、88.42%、87.08%,抗体几何平均浓度(GMC)分别为1 180.57m IU/ml、78.57IU/ml、555.69IU/ml。麻疹和风疹抗体阳性率在各年龄组之间无显著性差异、各地区之间有显著性差异;流腮抗体阳性率在各年龄组之间有显著性差异,在地区之间无显著性差异。麻疹和流腮GMC在各年龄组和地区之间均有显著性差异,风疹GMC在各地区间有显著性差异,在年龄组之间无显著性差异。结论河南省健康人群麻疹、风疹、流腮抗体水平整体较高,需加强弱势区域和重点年龄组含麻疹、风疹、流腮成分疫苗的接种工作。
[Abstract]:Objective to investigate the antibody levels of measles, rubella and mumps (gills) in healthy population in Henan Province in 2016. Methods Blood samples were collected from 449 healthy persons from 8 age groups in 3 counties (districts) of Henan Province by systematic sampling. Serum measles, rubella and gills IgG antibodies were determined by Elisa. Results measles, rubella and rubella were detected in 449 subjects. The positive rates of gills antibody were 93.99m 88.42 and 87.08, respectively. The geometric mean concentration of antibodies (GMCs) was 1 180.57m IUP / ml 78.57 IUP / ml. There was no significant difference in the positive rates of measles and rubella antibodies among different age groups, but there were significant differences among different regions. The positive rate of gills antibody was significantly different among different age groups, but not among different regions. Measles and gills GMC had significant differences among different age groups and regions, and rubella GMC had significant difference among different regions. Conclusion the level of measles, rubella and gills antibody in healthy population in Henan Province is relatively high, and it is necessary to strengthen the vaccination of measles, rubella and gills in vulnerable areas and key age groups.
【作者单位】: 河南省疾病预防控制中心;
【分类号】:R511;R512.1
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