2012-2015年湖北省麻疹流行病学及病原基因特征

发布时间：2018-02-22 01:57

  本文关键词： 麻疹 基因 流行病学　出处：《中华疾病控制杂志》2017年06期 　论文类型：期刊论文

【摘要】：目的分析2012-2015年湖北省麻疹流行特征和病原基因特征,为制定消除麻疹策略提供依据。方法通过传染病报告系统和麻疹病例专报系统,收集2012-2015年湖北省麻疹报告病例,描述病例的时间、地区、年龄分布等特征,并对病毒基因型别进行分析。结果 2012-2015年,湖北省共报告麻疹病例3 258例,年平均发病率约为14.063/100万,2014和2015年发病率明显增高。2012-2015年每年麻疹的发病高峰不同。麻疹发病年龄主要以2岁的婴幼儿和≥15岁的成人为主。麻疹发病人群主要集中在散居儿童,其他依次是农民、家政家务、幼托儿童和学生。麻疹病原学监测发现2012-2015年湖北省麻疹病毒基因型主要为H1a亚型,仅发现一例D8亚型,存在少数疫苗相关病例。结论 2012-2015年湖北省麻疹发病率明显增高,麻疹病毒主要为H1a亚型,发现一例D8亚型。建议进一步加强麻疹疫情的监测,做好适龄儿童和流动务工人员的常规免疫和查漏补种。
[Abstract]:Objective to analyze the epidemiological characteristics and pathogenic gene characteristics of measles in Hubei Province from 2012 to 2015, and to provide the basis for the strategy of measles elimination. Methods through the infectious disease reporting system and the measles case reporting system, we collected the measles reported cases from 2012 to 2015 in Hubei Province. The time, region and age distribution of the cases were described, and the gene types of the virus were analyzed. Results from 2012 to 2015, 3 258 measles cases were reported in Hubei Province. The annual average incidence of measles was about 14.063 / 1 million in 2014 and 2015. The annual measles incidence peak was different in 2012-2015. The age of measles incidence was mainly 2 years old infants and adults 鈮，

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