2016年成都市麻疹抗体水平监测分析

发布时间：2018-02-28 00:04

本文关键词： 麻疹血清流行病学调查　出处：《现代预防医学》2017年21期 　论文类型：期刊论文

【摘要】：目的了解成都市健康人群麻疹抗体水平,评价麻疹疫苗免疫效果,为麻疹免疫决策提供科学依据。方法于2016年选取4个县区,调查887人,采用酶联免疫吸附试验法(ELISA)定量检测血清麻疹Ig G水平。结果监测对象中,麻疹抗体几何平均浓度(GMC)为424.34 mIU/ml(95%CI:366.54~482.14 mIU/ml),抗体阳性率为90.42%。1岁以上人群麻疹抗体阳性率为98.74%,年龄与麻疹抗体浓度之间呈负相关(r_s=-0.139,P0.001)。外来流动人员抗体阳性率(85.45%)与成都户籍(91.55%)比较,差异有统计学意义(X~2=6.612,P=0.01)。育龄期妇女麻疹GMC为635.19 mIU/ml,抗体阳性率高达到99.30%。结论成都市健康人群麻疹抗体水平较高,近年来高水平麻疹疫苗接种率是可信的。流动儿童麻疹疫苗的查漏补种应常抓不懈。同时没有必要在育龄期妇女中再次接种麻疹疫苗。
[Abstract]:Objective to understand the measles antibody level of healthy population in Chengdu, evaluate the effect of measles vaccine immunization, and provide scientific basis for measles immunization decision. Methods in 2016, 887 people were investigated in 4 counties and districts. Elisa method was used to detect serum measles IgG level quantitatively. The geometric mean concentration of measles antibody (GMC) was 424.34 mIU/ml(95%CI:366.54~482.14 / ml, the positive rate of measles antibody was 90.42.1 years old and the positive rate of measles antibody was 98.74. There was a negative correlation between age and measles antibody concentration. The difference was statistically significant (P < 0.01). The GMC of measles in women of childbearing age was 635.19 mm / ml, and the positive rate of measles antibody was as high as 99.300.Conclusion the level of measles antibody in healthy population of Chengdu is higher. In recent years, the high level of measles vaccine coverage rate is credible. It is not necessary to re-inoculate measles vaccine among women of childbearing age.
【作者单位】：成都市疾病预防控制中心;
【分类号】：R511.1

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