支气管内超声引导针吸活检术对肺门、纵隔淋巴结肿瘤和结核的诊断价值

发布时间：2018-02-28 05:46

本文关键词： 支气管内超声引导针吸活检术肺门纵膈淋巴结诊断　出处：《四川大学学报(医学版)》2017年03期 　论文类型：期刊论文

【摘要】：目的探讨支气管内超声引导针吸活检术(EBUS-TBNA)在肺门、纵膈淋巴结恶性肿瘤和结核诊断中的应用价值。方法回顾性分析2013年1月至2016年9月在四川大学华西医院呼吸内镜中心接受EBUSTBNA检查的553例患者的临床及病理资料,统计EBUS-TBNA对肺门、纵膈淋巴结肿瘤和结核的诊断敏感性、特异性和准确率。结果 EBUS-TBNA诊断肺门、纵膈淋巴结恶性肿瘤的敏感性、特异性和准确率分别为89.2%(263/295)、100.0%(247/247)和94.1%(510/542)。针吸活检组织查见肉芽肿诊断结核的敏感性、特异性和准确率分别为65.0%(76/117)、97.2%(385/396)和89.9%(461/513)。标本组织行抗酸染色和TB-PCR的102例中,查见抗酸杆菌或TB-PCR任一项阳性诊断结核的敏感性、特异性和诊断准确率为63.7%(58/91)、90.9%(10/11)和66.7%(68/102)。结论 EBUS-TBNA诊断肺门和纵膈肿瘤具有较高的敏感性和特异性,并可联合抗酸染色和TB-PCR联合诊断肺门和纵膈淋巴结结核。
[Abstract]:Objective to explore the role of EBUS-TBNA-EBUS-TBNAA in the pulmonary hilus. Methods from January 2013 to September 2016, the clinical and pathological data of 553 patients undergoing EBUSTBNA examination in the Center of Respiratory Endoscopy, West China Hospital, Sichuan University, were retrospectively analyzed. The sensitivity, specificity and accuracy of EBUS-TBNA in diagnosis of hilar and mediastinal lymph node tumors and tuberculosis were analyzed. Results the sensitivity of EBUS-TBNA in the diagnosis of hilar and mediastinal lymph node malignant tumors was evaluated. The specificity and the accuracy were 89. 2 / 263 / 295 100.010. 0 and 94. 1% 510 / 542, respectively. The specificity and accuracy of needle aspiration biopsy were 65. 0% 767% 97. 2% 3855% 396 and 89. 9% 461 513%, respectively. There were 102 cases of antacid staining and TB-PCR. The sensitivity, specificity and diagnostic accuracy of either positive acid-fast bacilli or TB-PCR for diagnosis of tuberculosis were 63.7% and 66.7%, respectively. Conclusion EBUS-TBNA has a high sensitivity and specificity in the diagnosis of hilar and mediastinal tumors. It can be combined with acid-fast staining and TB-PCR to diagnose hilar and mediastinal lymph node tuberculosis.
【作者单位】：四川大学华西医院呼吸与危重症医学科;
【基金】：国家自然科学基金(No.81372504) 四川省科技厅项目(No.2016CZYD0001)资助
【分类号】：R521;R734

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