重症埃博拉病毒病患者脏器功能损害与加强支持治疗的文献分析

发布时间：2018-03-25 03:35

本文选题：埃博拉病毒病　切入点：重症监护病房　出处：《第二军医大学学报》2015年08期

【摘要】：目的通过复习相关文献分析和总结重症埃博拉病毒病患者的脏器功能损害表现以及相应的支持治疗方法。方法检索Medline和EMbase数据库,选取2014年以来收治于重症监护病房(ICU)的重症埃博拉病毒病病例,收集患者的临床表现、治疗经过以及预后等资料,结合相关文献进行分析和总结。结果共检索到7篇病例研究,报告了10例重症埃博拉病毒病患者。几乎所有患者都伴发内环境紊乱、肝损伤、血小板降低。4例患者出现呼吸衰竭,其中3例伴有肾功能衰竭。患者在ICU中接受了不同程度的加强支持治疗,包括维持内环境稳定、输注血制品、有创或无创机械通气、肾脏替代治疗、抗病毒治疗等。9例患者康复出院,1例死亡。结论重症埃博拉病毒病患者常合并多脏器功能损害,经加强支持治疗后脏器功能可恢复,存活率大大提高。
[Abstract]:Objective to analyze and summarize the visceral dysfunction and the corresponding supportive treatment methods in patients with severe Ebola virus disease by reviewing the relevant literature. Methods Medline and EMbase databases were searched. Select the severe Ebola virus cases treated in intensive care unit (ICU) since 2014, collect the clinical manifestation, treatment process and prognosis of the patients, and analyze and summarize the relevant literature. Results A total of 7 case studies were retrieved. Ten patients with severe Ebola virus disease were reported. Almost all of them were accompanied by internal environment disorder, liver injury, thrombocytopenia and respiratory failure. Three of them were associated with renal failure. The patients received various levels of intensive support therapy in ICU, including maintenance of internal stability, transfusion of blood products, invasive or non-invasive mechanical ventilation, renal replacement therapy, Conclusion severe Ebola virus disease patients are often complicated with multiple organ function damage. The organ function can be recovered and the survival rate can be greatly improved after strengthened support therapy.
【作者单位】：中国人民解放军第二批援利医疗队;第二军医大学长海医院麻醉科;第二军医大学长海医院感染科;第二军医大学长海医院呼吸内科;
【分类号】：R512.8

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