模式识别受体在HBV感染过程中的作用研究进展

发布时间：2018-03-25 15:03

  本文选题：乙型肝炎病毒　切入点：模式识别受体　出处：《实用肝脏病杂志》2016年06期

【摘要】：乙型肝炎病毒感染后常可导致慢性乙型肝炎。机体模式识别受体(PRRs)作为一类重要的识别分子,在病毒感染早期可识别病原体并诱导抗病毒免疫应答。本文阐述了PRRs的定义、种类和信号通路,将其分为Toll样受体家族和Toll非依赖性模式识别受体家族,介绍了其与乙型肝炎病毒感染之间的关系。
[Abstract]:Hepatitis B virus infection often leads to chronic hepatitis B. as an important recognition molecule, organism pattern recognition receptor (PRRs) can recognize pathogens and induce antiviral immune response in the early stage of viral infection. This paper describes the definition of PRRs. The type and signal pathway were divided into Toll like receptor family and Toll independent pattern recognition receptor family. The relationship between them and hepatitis B virus infection was introduced.
【作者单位】： 安徽医科大学附属省立医院感染病科;南京医科大学第一附属医院感染病科;
【基金】：国家自然科学基金项目(编号:81271713) Gilead Sciences Research Scholars Program in Liver Disease亚洲项目
【分类号】：R512.62
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本文编号：1663639