CT肝脏体积对乙肝后肝硬化程度的量化诊断价值

发布时间：2018-03-25 14:24

  本文选题：乙肝后肝硬化　切入点：CT肝脏体积　出处：《山东医药》2017年16期

【摘要】：目的探讨CT肝脏体积在乙肝后肝硬化程度量化诊断的价值。方法选择乙肝后肝硬化患者30例,肝组织活检术前1周行64层螺旋CT薄层扫描+三期增强扫描,将获得的数据导入Mimics10.01软件,进行肝脏三维立体重建并计算CT肝脏体积。术前评估患者肝硬化临床分期,计算终末期肝病模型(MELD)评分。分析CT肝脏体积与肝组织病理分级、肝硬化临床分期和MELD评分的关系。结果 30例患者CT肝脏体积明显小于理论肝脏体积(P0.05)。肝组织病理分级4A、4B、4C级者,肝硬化临床分期1、2、3、4期者,MELD评分10分、≥10~20分、≥20~30分者CT肝脏体积比较差异均有统计学意义(P均0.05)。相关分析显示,肝组织病理分级、肝硬化临床分期和MELD评分均与CT肝脏体积呈负相关(r分别为-0.55、-0.78及-0.52,P均0.01)。结论CT肝脏体积可作为乙肝后肝硬化程度的一个量化诊断指标;CT肝脏体积越小,肝组织病理分级越重、临床分期等级越高、MELD评分越高。
[Abstract]:Objective to evaluate the value of CT liver volume in the quantitative diagnosis of liver cirrhosis after hepatitis B. methods Thirty patients with liver cirrhosis after hepatitis B were examined with three-phase enhanced spiral CT scanning one week before liver biopsy. The obtained data were imported into Mimics10.01 software to reconstruct the liver three-dimensional and calculate the CT liver volume. The clinical stage of liver cirrhosis was evaluated before operation, and the end stage liver disease model was evaluated. The liver volume and pathological grade of liver tissue were analyzed. Results the CT liver volume of 30 patients was significantly smaller than that of theoretical liver volume (P0.05). The difference of CT liver volume was statistically significant in patients with liver volume 鈮，

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