2011—2015年上海市支原体感染及其耐药情况分析

发布时间：2018-04-03 02:41

本文选题：解脲脲原体　切入点：人型支原体　出处：《实用皮肤病学杂志》2016年05期

【摘要】：目的了解上海市解脲脲原体(ureaplasma urealyticum,UU)和人型支原体(mycoplasma hominis,MH)感染及其耐药情况,为有效防治支原体感染提供可靠的依据。方法收集2011年1月—2015年12月本院泌尿生殖道标本9 074份,使用支原体培养鉴定计数药敏试剂盒对其进行检测及药敏试验。结果支原体阳性3 238份(占35.68%),其中UU阳性2 505份(占27.61%)。女性宫颈分泌物、男性尿道分泌物及男性精液支原体阳性率依次为53.19%、33.55%、13.61%。男性和女性分别在26~30岁和16~20岁年龄段支原体阳性率最高。除交沙霉素外,多数大环内酯类药物对UU+MH阳性和MH阳性的耐药率均较高。四环素类药物对UU+MH阳性、UU阳性和MH阳性三者的敏感率均较高(95%)。结论上海地区泌尿生殖道支原体感染以UU为主,在性活跃的人群中高发,且与男性不育有关联。在临床治疗中,可优先考虑采用四环素类药物。
[Abstract]:Objective to investigate the infection and drug resistance of Ureaplasma Urealyticum Ureaplasma Urealyticum Urealyticum Ureaplasma Urealyticum Urealyticum Ureaplasma Urealyticum Urealyticum Ureaplasma Urealyticum Urealyticum Ureaplasma Urealyticum UrealyticumMethods from January 2011 to December 2015, 9 074 specimens of genitourinary tract in our hospital were collected and tested with Mycoplasma culture and count drug sensitivity kit.Results there were 3 238 positive cases of mycoplasma (35.68%), of which 2 505 were UU positive (27.61%).The positive rate of female cervical secretion, male urethral secretion and male semen mycoplasma were 53.19 and 33.55 respectively.The positive rate of mycoplasma was the highest in male and female aged 2630 and 1620, respectively.Except for josamycin, the resistance rates of most macrolides to UU MH and MH were higher.The sensitivity rate of tetracycline to UU MH positive and MH positive was higher than 95%.Conclusion Ureaplasma Urealyticum infection in the urogenital tract in Shanghai is mainly UU, and it is associated with male infertility.Tetracycline drugs may be given priority in clinical treatment.
【作者单位】：上海交通大学附属第六人民医院皮肤科;
【分类号】：R691.3

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