细菌性皮肤感染采用夫西地酸乳膏治疗的临床效果与安全性评价

发布时间：2018-04-04 20:02

  本文选题：夫西地酸乳膏　切入点：细菌性皮肤感染　出处：《中华医院感染学杂志》2015年02期

【摘要】：目的观察细菌性皮肤感染采用夫西地酸乳膏治疗的临床疗效和安全性,寻找细菌性皮肤感染的有效治疗方法。方法选取364例细菌性皮肤感染患者作为研究对象,将患者随机分为试验组和对照组,各182例,试验组患者每日外用夫西地酸乳膏涂药3次,7d为1个疗程,渗出性皮损患者先用1∶10 000高锰酸钾溶液清洗患处后再涂抹药膏;对照组患者每日外用莫匹罗星软膏涂抹3次,7d为1个疗程,治疗前及治疗期间不合并使用其他抗菌药物,对比两组患者的治疗效果。结果治疗后试验组金黄色葡萄球菌、链球菌属、棒杆菌属及3种菌混合感染患者的清除率分别为83.6%、57.1%、63.6%和60.0%;对照组分别为51.5%、40.7%、33.3%和30.0%,两组比较差异有统计学意义(P0.05);试验组显效率为53.3%、总有效率为96.7%,对照组分别为22.5%、75.3%,两组比较差异均有统计学意义(P0.05);试验组有174例患者对夫西地酸乳膏敏感,敏感率为95.6%,对照组132例患者对莫匹罗星软膏敏感,敏感率为72.5%,两组比较差异有统计学意义(P0.05)。结论夫西地酸乳膏对细菌性皮肤感染患者的治疗效果良好,且无明显的不良反应,同时患者对夫西地酸乳膏的敏感性较高。
[Abstract]:Objective to observe the clinical efficacy and safety of treating bacterial skin infection with Fusidi acid cream, and to find an effective treatment method for bacterial skin infection.Methods 364 patients with bacterial skin infection were randomly divided into experimental group (n = 182) and control group (n = 182).The patients with exudative lesions were first cleaned with potassium permanganate solution at 1:10 before applying ointment, while the patients in the control group were treated with mupiroxine ointment 3 times a day for 7 days as a course of treatment, and no other antibiotics were used before and during the treatment.The therapeutic effects of the two groups were compared.Results after treatment, Staphylococcus aureus and Streptococcus in the experimental group,妫掓潌鑿屽睘鍙，

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