发热伴血小板减少综合征患者血小板输注疗效分析

发布时间：2018-04-04 23:40

本文选题：发热伴血小板减少综合征　切入点：血小板输注　出处：《中国输血杂志》2017年09期

【摘要】：目的探讨发热伴血小板减少综合征(SFTS)患者血小板输注的疗效和可能存在的影响因素,为提高临床血小板输注疗效提供理论依据。方法选择在本院确诊,接受治疗并进行血小板输注的30例SFTS患者为研究对象,其中男性17例,女性13例,平均年龄57.5岁。通过比较血小板输注前后患者PT、APTT、TT变化,分析输注血小板后患者凝血功能改变状况;测定血小板输注前1 h和输注后24 h外周血血小板的数量,计算PPR和CCI,评价血小板输注效果。结果与血小板输注前相比,患者输注血小板24 h后血小板数量明显增加,APTT、TT时间显著缩短;随着患者输注血小板次数的增多,血小板输注有效率下降。结论 SFTS患者输注血小板之后,凝血功能得到改善;随着血小板输注次数的增多,血小板输注有效率下降,无效率明显增高;非免疫性因素可能对SFTS患者血小板输注疗效有较大影响。
[Abstract]:Objective to investigate the fever with thrombocytopenia syndrome (SFTS) patients factors and efficacy of platelet transfusion may exist, and provide theoretical basis for improving the clinical curative effect of platelet transfusion. Methods in our hospital diagnosed, treated and platelet transfusion in 30 cases of SFTS patients as the research object, including 17 cases of men. 13 women with an average age of 57.5 years. Through the comparison of platelet transfusion in patients before and after PT, APTT, TT change, change the situation analysis of transmission of blood coagulation in patients with platelet transfusion; Determination of platelet transfusion before 1 h and 24 h transmission and platelet count in peripheral blood after injection, the calculation of PPR and CCI, to evaluate the effects of platelet transfusion results compared with platelet transfusion before transfusion in the number of platelet platelet increased significantly after 24 h, APTT, TT could significantly shorten the time; with the increase of the number of patients with platelet infusion, the platelet transfusion efficiency decreased. Conclusion the patients with SFTS After transfusion of platelet, the coagulation function was improved. With the increase of platelet transfusion times, the efficiency of platelet transfusion decreased and the inefficiency increased significantly. Non immune factors may have a great effect on platelet transfusion efficacy in SFTS patients.

【作者单位】：青岛市第六人民医院;
【分类号】：R457.1;R510

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