MSM的HIV感染危险因素的交互作用研究

发布时间：2018-05-05 19:37

本文选题：男男性行为人群 + 艾滋病病毒　；参考：《中国艾滋病性病》2015年02期

【摘要】：目的研究男男性行为人群(MSM)感染艾滋病病毒(HIV)的危险因素及其交互作用,为艾滋病干预提供科学依据。方法 2013年7月至2014年2月,在深圳市慢性病防治中心MSM项目门诊和夕颜文化传播中心MSM关爱室,招募MSM进行一对一的问卷调查,并采集5~10mL外周静脉血检测HIV和梅毒抗体。以HIV感染状况为因变量,人口学特征、艾滋病知识知晓情况、梅毒感染状况、性行为状况等为自变量,进行单因素和多因素非条件Logistic回归分析,在此基础上进行交互作用分析。结果共调查406名MSM,完成调查的369名MSM,有效率90.9%。低文化程度、梅毒感染、自认感染风险低、正确用安全套能否预防HIV(安全套预防认知)、肛交角色为被动方,是MSM发生HIV感染的危险因素,梅毒与学历之间、固定性伴与网络寻找性伴之间、肛交角色与肛交用套之间存在交互作用,性取向分别与居住状态、梅毒、性病史之间存在交互作用。结论 MSM的HIV感染是多种危险因素引起的,各危险因素之间的交互作用更提示MSM艾滋病防治的复杂性,对其干预应采取综合措施。
[Abstract]:Objective to study the risk factors and interaction of MSM infection with HIV / AIDS in MSM and to provide scientific evidence for HIV / AIDS intervention. Methods from July 2013 to February 2014, MSM was recruited to carry out a one-to-one questionnaire survey in the MSM project clinic of Shenzhen chronic Disease Control Center and MSM Care Room of Xiyan Cultural Communication Center, and the peripheral venous blood samples of 5~10mL were collected for detection of HIV and syphilis antibody. With HIV infection as dependent variable, demographic characteristics, knowledge of AIDS, syphilis infection and sexual behavior as independent variables, univariate and multivariate unconditioned Logistic regression analysis was carried out, and interaction analysis was carried out on this basis. Results 406 MSMs were investigated and 369 MSMs were completed. The effective rate was 90.9. Low education, syphilis infection, low risk of infection, whether correct use of condom can prevent HIV (condom prevention cognition, anal sex role as passive side, is the risk factor of HIV infection in MSM, between syphilis and educational background. There were interactions between fixed sex partners and network search partners, between anal sex roles and anal intercourse sets, and between sexual orientation and living status, syphilis, and sexual history. Conclusion the HIV infection of MSM is caused by many risk factors, and the interaction among the risk factors indicates the complexity of MSM AIDS prevention and treatment, and comprehensive measures should be taken to prevent and treat MSM AIDS.
【作者单位】：中南大学公共卫生学院;深圳市慢性病防治中心;广东省皮肤性病防治中心;深圳市南山区慢性病防治院;
【基金】：国家自然科学基金(81271504)~~
【分类号】：R512.91

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