浅析化疗疗程对肾结核治疗效果的影响

发布时间：2018-05-05 20:15

本文选题：化疗疗程 + 复发率　；参考：《中国现代药物应用》2016年23期

【摘要】：目的分析化疗疗程对肾结核治疗效果的影响。方法 120例肾结核患者,根据24 h双肾彩超下肾内病灶吸收情况和尿结核菌检查阴转情况分别进行9~24个月化疗,对疗程结束后的复发率与治疗效果进行分析。结果将120例患者按化疗疗程分为四组,每组30例,化疗12、18、24个月后停药1年内复发率(30.00%、10.00%、0)显著低于化疗9个月后停药1年内复发率(63.33%),差异均具有统计学意义(P0.05)。将120例患者按不同强化期分为四组,每组30例,强化期4、6个月24 h尿结核阴转率(36.67%、56.67%)显著优于强化期2个月24 h尿结核阴转率(3.33%),差异均具有统计学意义(P0.05)。结论肾结核具有特殊性,应由专业医生根据患者的病情以及临床实践制定治疗方案,适当延长化疗疗程与强化期,能够有效增加尿结核阴转率,降低停药1年内复发率,值得临床上运用。
[Abstract]:Objective to analyze the effect of chemotherapy course on renal tuberculosis. Methods 120 patients with renal tuberculosis were treated with chemotherapy for 924 months according to the absorption of renal focus and the negative change of urinary tuberculous bacilli under 24 h color Doppler sonography. The recurrence rate and therapeutic effect were analyzed after the end of the course of treatment. Results 120 patients were divided into four groups according to the course of chemotherapy, 30 cases in each group. The recurrence rate of 30.0010. 00% was significantly lower than that of 1 year after 9 months of chemotherapy. The difference was statistically significant (P 0.05). 120 patients were divided into four groups according to different enhancement stages, 30 cases in each group. The negative conversion rate of urinary tuberculosis was 36.67% and 56.67% at 24 h after 4 and 6 months of enhancement. The negative conversion rate of urinary tuberculosis was significantly higher than that of 2 months and 24 hours after enhancement period. The difference was statistically significant (P 0.05). Conclusion Renal tuberculosis has its particularity. According to the patient's condition and clinical practice, the professional doctor should make the treatment plan, prolong the chemotherapy course and strengthen the period appropriately, can effectively increase the negative turn rate of urinary tuberculosis and reduce the recurrence rate within 1 year after the withdrawal of the drug. It is worthy of clinical application.
【作者单位】：丰顺县慢性病防治院;
【分类号】：R527.1

【参考文献】