驱梅治疗时机对妊娠合并梅毒患者妊娠结局、围产儿健康及先天性梅毒发生率的影响

发布时间：2018-05-08 05:48

本文选题：驱梅治疗 + 妊娠　；参考：《临床医学研究与实践》2017年32期

【摘要】：目的探讨驱梅治疗时机对妊娠合并梅毒患者妊娠结局、围产儿健康及先天性梅毒发生率的影响。方法选取2011年6月至2012年6月我院收治的162例妊娠合并梅毒患者为研究对象,将行驱梅治疗的97例患者作为观察组,将未行驱梅治疗的65例患者作为对照组。根据不同驱梅时机将观察组患者分为孕早期组(n=29)、孕中期组(n=35)及孕晚期组(n=33);根据梅毒程度将所有患者分为潜伏组(n=64)、I期组(n=49)、II期组(n=31)及晚期组(n=18)。观察不同组别患者的妊娠结局、围产儿健康及先天性梅毒发生率。结果观察组的早产儿、先兆流产、先天性梅毒患儿、极低体重儿、新生儿死亡的发生率明显低于对照组(P0.05)。孕早期组和孕中期组早产儿、先兆流产、先天性梅毒患儿、极低体重儿、新生儿死亡的发生率明显低于孕晚期组(P0.05)。潜伏期组、I期组及晚期组的早产儿、先兆流产、先天性梅毒、患儿、极低体重儿、新生儿死亡的发生率明显低于II期组,差异有统计学意义(P0.05)。结论妊娠合并梅毒患者容易出现不良妊娠结局,影响孕妇和围产儿的生命健康,因此应尽早进行驱梅治疗,能保障围产儿的健康,并有效地降低先天性梅毒的发生率,避免不良妊娠结局的发生。
[Abstract]:Objective to investigate the effect of the treatment time on pregnancy outcome, perinatal health and incidence of congenital syphilis in pregnant women with syphilis. Methods from June 2011 to June 2012, 162 pregnant women with syphilis were selected as the study object, 97 patients treated with exfoliation as the observation group and 65 patients without the treatment as the control group. The observation group was divided into two groups according to the different time of driving out the plum: early pregnancy group, second trimester group and late pregnancy group. According to the degree of syphilis, all the patients were divided into two groups: the latent group, the stage I group, and the late group, group N1818. Pregnancy outcomes, perinatal health and incidence of congenital syphilis were observed in different groups of patients. Results the incidence of premature infants, threatened abortion, congenital syphilis and very low birth weight infants in the observation group was significantly lower than that in the control group (P 0.05). The incidence of premature infants, threatened abortion, congenital syphilis and very low birth weight infants in the early and second trimester groups was significantly lower than that in the late pregnancy group (P 0.05). The incidence of premature infants, threatened abortion, congenital syphilis, infantile infants, very low birth weight infants, and neonatal death in stage I and late stage group was significantly lower than that in stage II group, the difference was statistically significant (P 0.05). Conclusion pregnant women with syphilis are prone to adverse pregnancy outcomes, which may affect the life and health of pregnant women and perinatal infants. Therefore, early treatment should be carried out to protect perinatal health and effectively reduce the incidence of congenital syphilis. Avoid adverse pregnancy outcomes.
【作者单位】：周至县人民医院;澄合矿务局中心医院;
【分类号】：R759.154

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