派特灵治疗男性尿道口尖锐湿疣的疗效观察

发布时间：2018-05-13 20:21

本文选题：尖锐湿疣 + 派特灵　；参考：《吉林大学》2017年硕士论文

【摘要】：背景:尖锐湿疣是由人乳头瘤病毒感染引起的临床中常见的一种性传播疾病,常表现为生殖器及肛周部位乳头状、菜花状、鸡冠状增生物。本病具有潜伏周期长、传染性强、复发率高等特征。因其具有较高的复发率而对患者的日常工作和生活造成了很大的困扰,并影响了患者的心理健康。因此临床中应尽可能的降低患者的复发率而减轻患者的痛苦。本文通过观察派特灵和光动力治疗男性尿道口尖锐湿疣的疗效,进而对临床治疗提供指导。目的:观察派特灵和光动力治疗男性尿道口尖锐湿疣的临床疗效。方法:我科门诊确诊的76例男性尿道口尖锐湿疣患者,随机分为观察组和对照组。观察组应用派特灵治疗,对照组应用光动力疗法治疗。要求患者每半个月复诊一次,观察其是否复发。连续随访3个月,观察患者治疗的疗效。结果:治疗后,观察组治愈率为87.5%,总有效率为97.5%。对照组治愈率为80.5%,总有效率为94.4%。两组差异不具有统计学意义(P0.05)。治疗期间两组均未发生明显不良反应。结论:1.中药制剂派特灵治疗男性尿道尖锐湿疣临床疗效显著,复发率低,安全性好,在尖锐湿疣的治疗中具有较高的临床意义,值得进一步研究与推广。2.对于尿道口等特殊部位的尖锐湿疣,派特灵与光动力疗法疗效相当。
[Abstract]:Background: condyloma acuminatum is a common sexually transmitted disease caused by human papillomavirus infection. The disease is characterized by long latent period, strong infectivity and high recurrence rate. Because of its high recurrence rate, it causes great troubles to patients' daily work and life, and affects the patients' mental health. Therefore, the recurrence rate should be reduced as much as possible and the pain should be alleviated. The therapeutic effect of Peterin and photodynamic therapy on male urethral condyloma acuminatum was observed. Objective: to observe the clinical effect of Peterin and photodynamic therapy on male urethral condyloma acuminatum. Methods: 76 male patients with condyloma acuminatum at urethral orifice were randomly divided into observation group and control group. The observation group was treated with peterin and the control group with photodynamic therapy. Patients were asked to return every half a month to see if they recurred. The patients were followed up for 3 months to observe the therapeutic effect. Results: the cure rate was 87.5 and the total effective rate was 97.5in the observation group. In the control group, the cure rate was 80.5 and the total effective rate was 94. 4%. The difference between the two groups was not statistically significant (P 0.05). There were no obvious adverse reactions in both groups during the treatment. Conclusion 1. The treatment of male urethral condyloma acuminatum with Chinese medicine Paterin has a significant clinical effect, low recurrence rate and good safety. It has a high clinical significance in the treatment of condyloma acuminatum, and deserves further study and popularization. For condyloma acuminatum at special sites such as urethral orifices, Petrin is equivalent to photodynamic therapy.
【学位授予单位】：吉林大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R752.53

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