糖尿病患者血源性感染的临床特征研究

发布时间：2018-05-19 09:53

本文选题：糖尿病 + 血源性感染　；参考：《中华医院感染学杂志》2015年08期

【摘要】：目的探讨糖尿病并发血源性感染患者的病原学分布和临床特征,以指导临床诊断和治疗。方法回顾性分析2011年10月-2014年5月因发热入院并且血培养呈阳性的150例糖尿病患者临床资料,按照是否为脓毒血症分为脓毒症组42例和非脓毒症组108例,对比两组患者临床指标,采用SPSS 17.0软件进行统计分析。结果 150例患者中共42例发生脓毒血症,发生率为28.00%;共检出192株病原菌,以大肠埃希菌为主,共77株占40.1%;脓毒血症组的总胆固醇、高密度脂蛋白胆固醇、低密度脂蛋白胆固醇显著低于非脓毒血症组(P0.05);两组患者之间的原发感染部位相比差异无统计学意义。结论糖尿病并发血源性感染以大肠埃希菌和葡萄球菌属最为常见,糖尿病并发脓毒症以肺炎克雷伯菌最常见,脓毒症组和非脓毒症组具有不同的临床特征,临床诊治时应引起重视。
[Abstract]:Objective to investigate the etiological distribution and clinical characteristics of diabetes mellitus complicated with hematogenous infection in order to guide clinical diagnosis and treatment. Methods the clinical data of 150 patients with diabetes mellitus who were admitted to hospital for fever from October 2011 to May 2014 were retrospectively analyzed. According to whether they were sepsis or not, they were divided into sepsis group (n = 42) and non-sepsis group (n = 108). The clinical indexes of the two groups were analyzed by SPSS 17.0 software. Results A total of 42 cases (28.00%) of sepsis were found in 150 patients, 192 strains of pathogenic bacteria were detected, mainly Escherichia coli, 77 strains (40.1%), total cholesterol, high density lipoprotein cholesterol (HDL-C) in the sepsis group, total cholesterol (TC), high density lipoprotein cholesterol (HDL-C), and high density lipoprotein cholesterol (HDL-C) in the sepsis group. Low density lipoprotein cholesterol (LDL-C) was significantly lower than that in non-sepsis group (P 0.05), and there was no significant difference in primary infection sites between the two groups. Conclusion Escherichia coli and Staphylococcus are the most common hematogenous infections in diabetes mellitus. Klebsiella pneumoniae is the most common type of diabetes mellitus complicated with sepsis, and sepsis and non-sepsis have different clinical characteristics. Attention should be paid to clinical diagnosis and treatment.
【作者单位】：孝感市第一人民医院内分泌科;
【基金】：湖北省卫生厅科研基金资助项目(JX4B25)
【分类号】：R587.1;R515.3

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