早期大鼠肝泡状棘球蚴病模型的超声表现与病理对照

发布时间：2018-05-19 16:29

本文选题：泡状棘球蚴 + 肝　；参考：《中国介入影像与治疗学》2015年08期

【摘要】：目的探讨大鼠早期肝泡状棘球蚴病模型的超声特征。方法对接种肝泡状棘球蚴9周且健康存活的157只大鼠进行超声检查,记录大鼠早期肝泡状棘球蚴病的超声表现,并与病理结果对照。评价超声筛查早期大鼠肝泡状棘球蚴病的效能。结果超声筛查早期大鼠肝泡状棘球蚴病模型敏感度(130/139,93.53%)和特异度(15/18,83.33%)均较高。早期大鼠肝泡状棘球蚴病灶超声主要表现为高回声(114/142,80.28%),19.72%(28/142)的病灶表现为混合性回声。病灶大体病理表现为米黄色或乳白色囊泡样结构,呈针尖样或多囊泡状,内含囊液;HE染色呈中央红染纤维结构,周边环以微小血管及炎性细胞。结论早期大鼠肝泡状棘球蚴病灶的超声主要表现为高回声伴或不伴无回声及低回声囊泡样结构,超声筛查早期大鼠肝泡状棘球蚴病模型具有很高的敏感度。
[Abstract]:Objective to investigate the ultrasonic characteristics of early hepatic alveolar echinococcosis in rats. Methods 157 healthy rats inoculated with hepatic alveolar hydatid for 9 weeks were examined by ultrasound, and the ultrasonographic findings of early hepatic alveolar echinococcosis were recorded and compared with pathological results. Objective: to evaluate the efficacy of ultrasonography in screening early rat hepatic alveolar echinococcosis. Results the sensitivity and specificity of the early rat model of hepatic alveolar echinococcosis were 130 / 139 / 93.53 and 15 / 1883.33, respectively. In the early stage of hepatic alveolar echinococcosis in rats, the focus of hydatid was characterized by mixed echo, which was 114 / 142.80.28% and 19.72% / 142respectively. The pathological features of the lesions were beige or milkish white vesicles, needle tip or polycystic vesicles, central red stained fibers with HE staining of cystic fluid, and small blood vessels and inflammatory cells around the circumference. Conclusion the ultrasonic findings of early rat hepatic alveolar hydatid lesions are mainly hyperechoic with or without anechoic and hypoechoic vesicular structure. Ultrasound screening of early rat liver alveolar echinococcosis model has a high sensitivity.
【作者单位】：新疆医科大学第一附属医院超声诊断科;新疆医科大学第一附属医院新疆包虫病基础医学重点实验室;新疆医科大学第一附属医院影像中心;
【基金】：新疆自治区自然科学基金(2014211C039)
【分类号】：R-332;R532.32;R445.1

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