乙肝肝硬化患者剪切波弹性测量值与Child-Pugh分级的相关性研究

发布时间：2018-05-20 18:50

本文选题：肝硬化 + Child-Pugh分级　；参考：《中国超声医学杂志》2017年08期

【摘要】：目的探讨慢性乙肝肝硬化患者Child-Pugh分级与肝脏剪切波弹性测量值的相关性。方法收集住院的乙肝肝硬化患者108例,其中Child-Pugh A级48例,Child-Pugh B级32例,Child-Pugh C级28例。所有患者均测量肝脏组织的杨氏模量值,比较不同Child-Pugh分级患者肝组织的杨氏模量值差异,并分析各项杨氏模量值参数与Child-Pugh评分的相关性。结果随着Child-Pugh分级的增加,肝组织杨氏模量值的各项参数均逐渐升高,不同级别患者之间的各项杨氏模量值参数差异均有统计学意义。Child-Pugh评分与肝组织杨氏模量值的各项参数均呈正相关,相关系数分别为平均值r=0.597、最小值r=0.603、最大值r=0.583。结论乙肝肝硬化患者剪切波弹性测量值与Child-Pugh分级有一定的相关性,能在一定程度上反映肝功能的储备情况。
[Abstract]:Objective to investigate the correlation between Child-Pugh grading and shear wave elasticity in patients with chronic hepatitis B cirrhosis. Methods one hundred and eight inpatients with hepatitis B cirrhosis were collected, including 48 patients with Child-Pugh A and 32 patients with Child-Pugh B with Child-Pugh C. The Young's modulus of liver tissue was measured in all patients, and the difference of Young's modulus in different Child-Pugh grade patients was compared, and the correlation between the parameters of Young's modulus and Child-Pugh score was analyzed. Results with the increase of Child-Pugh grade, the parameters of Young's modulus of liver tissue increased gradually. There were significant differences in the parameters of Young's modulus between patients with different grades. Child-Pugh score was positively correlated with the parameters of Young's modulus of liver tissue, and the correlation coefficients were average r = 0.597, minimum r = 0.603, maximum r = 0.583respectively. Conclusion there is a certain correlation between shear wave elasticity and Child-Pugh grading in patients with hepatitis B cirrhosis, which can reflect the liver function reserve to some extent.
【作者单位】：中国医科大学附属第一医院超声科;
【分类号】：R445.1;R512.62;R575.2

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