神经梅毒治疗后血清RPR替代脑脊液检查的可行性
发布时间:2018-05-22 10:43
本文选题:神经梅毒 + RPR滴度 ; 参考:《南京医科大学学报(自然科学版)》2017年11期
【摘要】:目的 :研究神经梅毒治疗后快速血浆反应素试验(rapid plasma reagin test,RPR)滴度变化替代脑脊液检测预测疗效的可行性。方法:治疗47例符合条件的神经梅毒患者后,记录6个月的血清RPR滴度及脑脊液异常,并分析治疗前不同血清RPR滴度下有效预测值的差异。结果 :治疗后6个月,26例(55.3%)患者血清RPR治疗有效,37例(78.7%)患者脑脊液异常治疗有效,治疗前血清RPR≥1∶16的患者组血清RPR滴度变化更能预测脑脊液异常的变化。结论:在高血清滴度的患者中,血清RPR可以替代脑脊液检查预测神经梅毒患者的疗效,避免过多腰椎穿刺检查。
[Abstract]:Aim: to study the feasibility of rapid plasma reactivity test (RPR) titer of rapid plasma reactivity test (RPR) in alternative cerebrospinal fluid (CSF) detection after neurosyphilis treatment. Methods: after treatment of 47 patients with neurosyphilis, the serum RPR titers and cerebrospinal fluid (CSF) abnormalities were recorded for 6 months, and the difference of effective predictive values under different serum RPR titers before treatment was analyzed. Results: serum RPR was effective in 37 patients with cerebrospinal fluid abnormality 6 months after treatment. The changes of serum RPR titer in patients with serum RPR 鈮,
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