2012-2015年江苏省急性弛缓性麻痹病例特征分析

发布时间：2018-05-31 16:23

本文选题：急性弛缓性麻痹 + 临床症状　；参考：《现代预防医学》2017年14期

【摘要】：目的调查分析江苏省1 143例急性弛缓性麻痹(AFP)病例的一般情况、临床症状与随访情况,提高AFP的发现能力和诊断水平。方法采用随访和查阅病历的方式获取资料,计数资料采用率和构成比进行统计描述,采用卡方检验进行统计检验。结果江苏省2012-2015年AFP报告发病率2.57/10万,双下肢麻痹的占43.74%,单侧上下肢均麻痹的占33.16%,四肢麻痹的占14.09%。发热、腹泻等临床症状并无明显季节性,性别差异无统计学意义(P0.05)。肌肉疼痛、肢体感觉障碍和深部腱发射减弱或消失在≥5岁组病例中高于5岁组(P0.05)。麻痹后60 d随访,12.51%的病例有残留麻痹。结论 5岁的男性是AFP的高发人群。麻痹部位以下肢最为常见,麻痹前多伴有发热和肌肉疼痛。约有9成的AFP病例会在麻痹60 d内恢复,有残留麻痹的病例中麻痹严重程度也有所好转,但对有残留麻痹的AFP病例仍应重点关注。
[Abstract]:Objective to investigate and analyze the general situation, clinical symptoms and follow-up of 1 143 cases of acute flaccid paralysis (AFP) in Jiangsu Province, so as to improve the detection ability and diagnostic level of AFP. Methods data were obtained by following up and consulting the medical records. The statistical description of the rate and composition ratio of the counting data was carried out, and the chi-square test was used to carry out the statistical test. Results the reported incidence of AFP in Jiangsu Province from 2012 to 2015 was 2.57 / 100 thousand. The incidence of paralysis of both lower extremities was 43.74, that of both upper and lower extremities was 33.16, and that of limb paralysis was 14.099.Results the incidence of AFP from 2012 to 2015 in Jiangsu Province was 2.57%. Fever, diarrhea and other clinical symptoms were not significantly seasonal, the gender difference was not statistically significant (P 0.05). Muscle pain, limb sensory disturbance, and deep tendon emission decreased or disappeared in patients aged more than 5 years than in 5 years old group (P 0.05). Residual paralysis was found in 12.51% of the cases 60 days after palsy. Conclusion the 5-year-old male is a high risk group of AFP. Paralysis is most common in the lower extremities, with fever and muscle pain before paralysis. About 90% of AFP cases will recover within 60 days of paralysis, and the severity of paralysis in patients with residual paralysis will also be improved. However, attention should be paid to the cases of AFP with residual paralysis.
【作者单位】：江苏省疾病预防控制中心免疫规划所;
【基金】：江苏省卫生计生委科研课题(H201515)
【分类号】：R512.4

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