辽宁省丹东市两例间日疟病例报告疫情分析

发布时间：2018-06-06 11:10

本文选题：间日疟 + 疫情　；参考：《中国公共卫生》2017年02期

【摘要】：目的对辽宁省丹东市2015年8月发生的2例间日疟疫情调查处置进行描述和分析,指导继续开展消除疟疾工作。方法收集病例基本信息、流行病学资料、疫点自然情况、媒介监测情况等;收集本次疫情及既往间日疟病例全血,针对间日疟裂殖子表面蛋白基因进行套式PCR扩增并对产物测序分析。结果 2例病例为间日疟病例,主动病例搜索快速检测试验(RDT)检测病例周围居民467人,PCR检测103人,结果均为阴性;表面蛋白基因测序分析显示本次2例病例病原体间日疟裂殖子核酸序列高度同源,而与本省前几年本地病例则同源性不高,感染来源难以确定。结论 2例病例为本地感染病例,丹东地区存在传疟媒介,下一步应加大监测力度,继续调查感染来源;同时密切关注输入性病例,防止二代传播。
[Abstract]:Objective to describe and analyze the investigation and disposal of two cases of vivax malaria in Dandong City Liaoning Province in August 2015 so as to guide the work of eliminating malaria. Methods to collect the basic information of the case, epidemiological data, the natural situation of the epidemic spot, the surveillance of the vector, and collect the whole blood of this epidemic situation and the past vivax malaria cases. The merozoite surface protein gene of Plasmodium vivax malaria was amplified by nested PCR and sequenced. Results two cases were vivax malaria cases. The positive case search rapid detection test (RDT) was used to detect 103 cases in 467 residents around the case, and the results were all negative. Surface protein gene sequencing analysis showed that the nucleic acid sequence of merozoite of vivax malaria was highly homologous in the two cases, but not homologous with the local cases in previous years, and the source of infection was difficult to determine. Conclusion two cases are local infection cases, there are malaria vectors in Dandong area, the next step should be to monitor the source of infection and pay close attention to imported cases to prevent the second generation transmission.
【作者单位】：辽宁省疾病预防控制中心传染与感染性疾病防制所;丹东市疾病预防控制中心;
【分类号】：R531.3

【相似文献】