HIV抗体筛查阳性标本中确证阴性比例及相关因素分析

发布时间：2018-06-20 13:40

本文选题：HIV抗体 + 酶联免疫吸附试验　；参考：《现代预防医学》2017年10期

【摘要】：目的了解HIV抗体ELISA检测阳性者确证阴性情况并分析相关因素。方法收集玉溪市ELISA筛查为HIV抗体阳性的2 127例标本的人口学特征、可能感染途径、样本来源及确证结果,计算确证阴性率并分析相关因素。结果确证阴性率为12.08%(257/2 127),其中女性、小于30岁年龄组、汉族、初中及以上文化程度者、已婚者、公职人员/退休职工、学生、样本来源于无偿献血、可能感染途径不详及母婴传播者确证阴性率较高,分别为19.39%(128/660),20.00%(96/480),13.93%(191/1 371)、15.84%(166/1 048),15.49%(177/1 143),23.00%(49/213),40.54%(15/37),70.67%(53/75),35.53%(140/394),23.53%(4/17)。多因素Logistic回归分析表明,女性(OR=1.888,95%CI:1.350~2.639)、年龄18岁组(OR=5.779,95%CI:1.762~18.956)、已婚者(OR=2.251,95%CI:1.394~3.634)、样本来源为无偿献血者(OR=7.620,95%CI:3.520~16.496)、可能感染途径不详者(OR=9.205,95%CI:5.900~14.360)HIV抗体ELISA阳性-确证阴性的可能更大。结论 HIV抗体筛查假阳性率在性别、年龄、婚姻状况、样本来源、可能感染途径中显著不同,相关工作人员对检测结果应进行合理的解释。
[Abstract]:Objective to investigate the confirmed negative status of HIV antibody positive patients by Elisa and to analyze the related factors. Methods the demographic characteristics of 2127 HIV antibody positive specimens screened by Elisa in Yuxi City were collected. The possible infection route, sample source and confirmed results were collected. The confirmed negative rate was calculated and the related factors were analyzed. Results the confirmed negative rate was 12.08g / 2127%, in which female, younger than 30 years old group, Han nationality, junior middle school and above education, married people, public servants / retired workers, students, samples from free blood donation, The possible route of infection is unknown and the confirmed negative rate of mother-to-child transmission is higher, which is 19.3988 / 660 / 20.00 / 96 / 480 and 13.933t / 1 3733n = 19.76 / 1,371/ 15.8445 / 1777 / 1,14323.004.49 / 41340.54 / 153.37 / 70.6753 / 7575 / 35.140 / 394r / 394r.394p / 394p / 3940 / r = 41717 / 417 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717 / 41717. The multivariate logistic regression analysis showed that the female ORA 1.88895 CI1.350 + 2.639, the age of 18 years old Or5.77995 CI1.762or 18.956, the married person 2.25195 CI1.3943.634, the sample from the unpaid blood donor OR7.62095CI3.52020 16.4966.O9.20595CI5.9005CI5.900 14.360 HIV antibody positive Elisa was more likely to be negative. Conclusion the false positive rate of HIV antibody screening is significantly different in sex, age, marital status, sample origin and possible infection pathway.
【作者单位】：云南省玉溪市疾病预防控制中心;
【分类号】：R512.91

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