2011-2013年淮安市职业暴露人群血清学和环境禽流感监测分析

发布时间：2018-07-16 21:23

【摘要】：目的了解淮安市职业暴露人群H5N1禽流感病毒抗体水平和环境中禽流感病毒的分布情况。方法采用血凝抑制试验检测职业暴露人群A(H5N1)血凝素抗体;采用Real-time PCR法对环境标本进行Flu A、H5、H7、H9禽流感病毒核酸检测。结果职业暴露人群240人份血清A(H5N1)抗体均为阴性;环境标本420份禽流感病毒核酸检测A型阳性率为0.71%。城乡活禽市场环境标本的阳性率为2.59%,其他监测场所未检出阳性标本,差异有统计学意义(Fisher确切概率χ2=5.64,P0.05),宰杀或摆放禽肉案板表面擦拭标本阳性率为13.04%,其他环境标本检测为阴性,差异有统计学意义(Fisher确切概率χ2=18.03,P0.01)。结论职业暴露人群血清标本中未检测出A(H5N1)禽流感病毒抗体阳性标本;淮安市监测点环境中存在H5、H9禽流感病毒;禽流感感染风险主要集中在城乡活禽市场。
[Abstract]:Objective to investigate the antibody level of H5N1 avian influenza virus and the distribution of avian influenza virus in environment of occupational exposed population in Huaian city. Methods A (H5N1) hemagglutinin antibody in occupational exposed population was detected by hemagglutination inhibition test and real-time PCR was used to detect the nucleic acid of avian influenza virus (Avian Influenza virus). Results A (H5N1) antibody was negative in 240 exposed population, and the positive rate of Avian Influenza virus type A in 420 environmental samples was 0.71%. The positive rate of environmental samples in live poultry market in urban and rural areas was 2.59 and no positive samples were detected in other monitoring sites (Fisher's exact probability 蠂 ~ (5.64) P 0.05). The positive rate of slaughtering or placing poultry meat table surface wiping specimens was 13.04, while that of other environmental samples was negative. The difference was statistically significant (Fisher exact probability 蠂 2: 18.03 P 0.01). Conclusion No positive samples of A (H5N1) avian influenza virus were detected in the serum samples of occupational exposed population, H5H9 avian influenza virus was found in the monitoring site environment of Huaian city, and the risk of avian influenza infection was mainly concentrated in the live poultry market in urban and rural areas.
【作者单位】：淮安市疾病预防控制中心;淮安市洪泽县疾病预防控制中心;淮安市金湖县疾病预防控制中心;
【分类号】：R511.7

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