142例亚临床型生殖器疱疹患者病毒脱排特点分析

发布时间：2018-07-25 15:14

【摘要】：目的分析亚临床型生殖器疱疹(GH)患者的病毒脱排特点,为临床治疗提供依据。方法选取2014年6月—2016年6月间我院收治的亚临床型GH患者142例,荧光定量PCR法检测患者单纯疱疹病毒(HSV)-DNA脱排情况,酶联免疫吸附试验(ELISA)检测患者血清Ig G抗体类型。分析年龄、性别、抗体类型及病程长短、发病频率对病毒脱排阳性率的影响。结果 142例患者中HSV-DNA阳性率为49.3%,女性的病毒脱排阳性率高于男性(P0.05)。血清HSV-ⅠIg G++HSV-ⅡIg G+与单纯HSV-ⅡIg G+患者病毒脱排阳性率差异无统计学意义,但二者均高于单纯HSV-ⅠIg G+患者。病程≤6年的患者病毒脱排阳性率高于6年者,频发患者(复发≥6次/年)高于少发患者(复发6次/年,均P0.05)。病程≤6年的患者中,频发患者高于少发患者,而病程6年的患者中,频发与少发患者病毒脱排阳性率差异无统计学意义(P0.05)。同时女性患者HSV-Ⅱ感染率高于男性(P0.05)。结论亚临床型GH患者的病毒脱排阳性率与性别、血清抗体类型、病程及发病频率等因素密切相关。
[Abstract]:Objective to analyze the characteristics of virus stripping in patients with subclinical genital herpes (GH) and to provide evidence for clinical treatment. Methods 142 patients with subclinical GH were selected from June 2014 to June 2016 in our hospital. The (HSV)-DNA desorption of herpes simplex virus (HSV) was detected by fluorescence quantitative PCR assay and the serum IgG antibody type was detected by Elisa (ELISA). The effect of age, sex, antibody type, duration of disease and frequency of disease on the positive rate of virus demagination was analyzed. Results the positive rate of HSV-DNA was 49.3% in 142 patients, and the positive rate of virus demagination in women was higher than that in men (P0.05). There was no significant difference between HSV- 鈪，

本文编号：2144213