HIV合并HBV感染之治疗进展
发布时间:2018-07-31 15:28
【摘要】:由于乙型肝炎病毒(HBV)、艾滋病病毒(HIV)具有相同的传播途径,HBV在感染HIV人群中的发生率较普通人群更高,在中国HBV高流行区域表现尤为明显。由于HIV和HBV合并感染会造成疾病进展加快,肝硬化、终末期肝病发生率较单纯HBV感染者更高。对于合并HBV之HIV感染者,若不开始抗反转录病毒治疗(ART)而单纯治疗HBV感染,用药需要注意避免诱发HIV耐药。开始ART时,用药选择宜兼顾HBV,治疗过程中若要换药,亦须保留对HBV有效之治疗用药。
[Abstract]:The incidence of hepatitis B virus (HBV),) (HIV) is higher than that of the general population, especially in the high prevalence area of HBV in China. As HIV and HBV co-infection can lead to faster progression of the disease, liver cirrhosis, end-stage liver disease incidence is higher than simple HBV infection. For HIV infected patients with HBV, it is necessary to avoid inducing HIV resistance if only HBV infection is treated only by antiretrovirus therapy instead of antiretroviral therapy. At the beginning of ART, the choice of drug should take account of HBV, and the effective drug for HBV should be retained in the course of treatment.
【作者单位】: 上海市(复旦大学附属)公共卫生临床中心感染科;复旦大学附属华山医院感染科;
【基金】:国家"十二五"传染病重大专项:艾滋病合并结核病规范化诊疗方案的推广及优化研究(2012ZX10001-003)~~
【分类号】:R512.91;R512.62
[Abstract]:The incidence of hepatitis B virus (HBV),) (HIV) is higher than that of the general population, especially in the high prevalence area of HBV in China. As HIV and HBV co-infection can lead to faster progression of the disease, liver cirrhosis, end-stage liver disease incidence is higher than simple HBV infection. For HIV infected patients with HBV, it is necessary to avoid inducing HIV resistance if only HBV infection is treated only by antiretrovirus therapy instead of antiretroviral therapy. At the beginning of ART, the choice of drug should take account of HBV, and the effective drug for HBV should be retained in the course of treatment.
【作者单位】: 上海市(复旦大学附属)公共卫生临床中心感染科;复旦大学附属华山医院感染科;
【基金】:国家"十二五"传染病重大专项:艾滋病合并结核病规范化诊疗方案的推广及优化研究(2012ZX10001-003)~~
【分类号】:R512.91;R512.62
【共引文献】
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