凉山州首次接受抗病毒治疗的AIDS病人死亡情况分析

发布时间：2018-08-01 12:01

【摘要】：目的了解四川省凉山州首次接受抗病毒治疗(ART)的艾滋病(AIDS)病人,因AIDS死亡的情况及其影响因素。方法对2005-2012年中国艾滋病ART信息管理系统中的5525例凉山州艾滋病病人的基本情况、死亡时间、治疗情况、CD+4T淋巴细胞(简称CD4细胞)计数检测结果等数据资料进行分析。结果共死亡430例,其中287例(66.7%)死于AIDS相关疾病。病人接受治疗时的平均年龄为(34.5±9.0)岁,男性占86.4%(248/287),经静脉吸毒感染占76.0%(218/287),从确认HIV抗体阳性到接受ART的时间平均为(21.0±19.1)个月,9.6%(26/271)的病例治疗前最近一年患有肺结核。按照世界卫生组织临床分期,50.4%(140/278)的病死病例在治疗开始时为临床I期;开始治疗时CD4细胞计数检测平均为(219.9±130.1)个/mm3,88.9%(240/270)在350个/mm3。34.1%(98/287)的病例开始治疗前3个月出现AIDS相关疾病/症状;平均时间为(12.7±10.6)个月。52.3%(150/287)是在治疗开始后的12个月内病死。不同性别、感染途径、临床分期、首次CD4细胞计数检测结果、治疗前最近一年是否患有肺结核的AIDS病人,其病死率的差异有统计学意义。结论因AIDS相关疾病死亡是凉山州接受ART病人死亡的主要原因;AIDS病人应定期进行随访和CD4细胞检测,及早接受ART。
[Abstract]:Objective to investigate the death of (ART) patients with (ART) in Liangshan prefecture of Sichuan province and its influencing factors. Methods the data of 5525 AIDS patients from 2005 to 2012 in China AIDS ART Information Management system were analyzed, such as the basic condition, the time of death, and the results of CD4T lymphocyte (CD4 cell) count in Chinese AIDS information management system from 2005 to 2012. Results A total of 430 cases died, of which 287 cases (66.7%) died of AIDS related diseases. The average age at the time of treatment was (34.5 卤9.0) years, male was 86.4% (248 / 287), intravenous drug use infection was 76.0% (218 / 287). The average time from positive HIV antibody to receiving ART was (21.0 卤19.1) months or 9.6% (26 / 271). According to the WHO clinical stage, 50.4% (140 / 278) of the patients died at the beginning of treatment, and the average CD4 cell count at the beginning of treatment was (219.9 卤130.1) / (88.9%) / (240 / 270). The average time was (12.7 卤10.6) months. 52.3% (150 / 287) died within 12 months after treatment. There were significant differences in the mortality of AIDS patients with pulmonary tuberculosis in the last year before treatment, including sex, route of infection, clinical stage, first CD4 cell count, and whether or not they had pulmonary tuberculosis in the last year before treatment. Conclusion death due to AIDS related diseases is the main cause of death in patients receiving ART in Liangshan Prefecture. Patients with AIDS should be followed up regularly and CD4 cells should be detected as soon as possible.
【作者单位】：凉山彝族自治州疾病预防控制中心;凉山彝族自治州第一人民医院;中国疾病预防控制中心性病艾滋病预防控制中心;
【基金】：中国-默沙东艾滋病防治合作项目(C-MAP)~~
【分类号】：R512.91

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