左氧氟沙星滴眼液联合复方血栓通胶囊对急性细菌性结膜炎患者疗效及清除细菌的作用分析
发布时间：2018-08-06 10:17
【摘要】：目的探讨急性细菌性结膜炎患者采用左氧氟沙星滴眼液联合复方血栓通胶囊治疗临床疗效,并观察其对细菌的清除效果。方法回顾性分析医院2013年12月-2015年12月急性细菌性结膜炎患者120例的诊治情况,其中采用0.5%左氧氟沙星滴眼液治疗者为对照组;于对照组治疗基础上采用复方血栓通胶囊治疗者为治疗组;双眼患者均选取右眼作为本次观察眼,单眼患者的另外眼需预防性用药。两组患者均治疗1周,于治疗后1d统计两组临床疗效,并通过采集标本进行细菌培养来判断细菌清除率;记录两组患者平均治愈时间及治疗期间所发生的不良反应。如治疗不到1周且患者临床症状、体征消失者可结束临床试验观察,并对药物疗效加以评价,按痊愈统计。对两组患者治疗期间所收集的数据均进行t或χ2检验。结果治疗组治疗临床有效率93.3%明显高于对照组75.0%,(P0.05);经细菌培养结果显示,治疗组与对照组分别培养60株,经治疗后,治疗组细菌清除率96.7%明显高于对照组83.3%,(P0.05)。治疗组平均治愈时间为(3.11±0.98)d明显短于对照组(6.47±1.22)d,(P0.05)。治疗期间两组均发生眼部瘙痒感和眼部刺激感,但症状较轻,未影响后续治疗及本研究结果。结论应用复方血栓通胶囊联合左氧氟沙星滴眼液治疗急性细菌性结膜炎临床疗效显著且安全,该方法可提高细菌清除率,加速患者康复,提高临床疗效。
[Abstract]:Objective to investigate the clinical efficacy of levofloxacin eye drops combined with compound Xuetong capsule in the treatment of acute bacterial conjunctivitis and to observe the effect of levofloxacin eye drops on bacterial clearance. Methods the diagnosis and treatment of 120 patients with acute bacterial conjunctivitis from December 2013 to December 2015 were retrospectively analyzed, among which 0.5% levofloxacin eye drops were used as the control group. On the basis of the treatment in the control group, the treatment group was treated with compound Xueshuantong capsule, the right eye was selected as the observation eye in both eyes, and the other eye of the monocular patient needed prophylactic medication. Two groups of patients were treated for one week, at 1 day after treatment, the clinical efficacy of the two groups was counted, and the bacterial clearance rate was determined by collecting samples for bacterial culture, and the average cure time and adverse reactions during the treatment were recorded. If the treatment is less than one week and the patient's clinical symptoms and signs disappear, the clinical trial observation can be finished, and the curative effect of the drug can be evaluated, according to the cure statistics. T or 蠂 2 tests were performed on the data collected during treatment in both groups. Results the clinical effective rate in the treatment group was 93.3% higher than that in the control group (P0.05), and the bacterial culture results showed that 60 strains were cultured in the treatment group and the control group, respectively. After treatment, the bacterial clearance rate in the treatment group was significantly higher than that in the control group (83.3%, P0.05). The average cure time in the treatment group was (3.11 卤0.98) days, significantly shorter than that in the control group (6.47 卤1.22) d, (, P0.05). The two groups developed eye itching and eye irritation during the treatment period, but the symptoms were mild and did not affect the follow-up treatment and the results of this study. Conclusion compound Xueshuantong capsule combined with levofloxacin eye drops is effective and safe in the treatment of acute bacterial conjunctivitis. This method can improve the bacterial clearance, accelerate the recovery of patients and improve the clinical efficacy.
【作者单位】： 解放军第一一七医院眼科;解放军第一一七医院心血管内科;
【基金】：浙江省医药卫生科技计划基金资助项目(2013KYA177)
【分类号】：R777.31
，
本文编号：2167421
[Abstract]:Objective to investigate the clinical efficacy of levofloxacin eye drops combined with compound Xuetong capsule in the treatment of acute bacterial conjunctivitis and to observe the effect of levofloxacin eye drops on bacterial clearance. Methods the diagnosis and treatment of 120 patients with acute bacterial conjunctivitis from December 2013 to December 2015 were retrospectively analyzed, among which 0.5% levofloxacin eye drops were used as the control group. On the basis of the treatment in the control group, the treatment group was treated with compound Xueshuantong capsule, the right eye was selected as the observation eye in both eyes, and the other eye of the monocular patient needed prophylactic medication. Two groups of patients were treated for one week, at 1 day after treatment, the clinical efficacy of the two groups was counted, and the bacterial clearance rate was determined by collecting samples for bacterial culture, and the average cure time and adverse reactions during the treatment were recorded. If the treatment is less than one week and the patient's clinical symptoms and signs disappear, the clinical trial observation can be finished, and the curative effect of the drug can be evaluated, according to the cure statistics. T or 蠂 2 tests were performed on the data collected during treatment in both groups. Results the clinical effective rate in the treatment group was 93.3% higher than that in the control group (P0.05), and the bacterial culture results showed that 60 strains were cultured in the treatment group and the control group, respectively. After treatment, the bacterial clearance rate in the treatment group was significantly higher than that in the control group (83.3%, P0.05). The average cure time in the treatment group was (3.11 卤0.98) days, significantly shorter than that in the control group (6.47 卤1.22) d, (, P0.05). The two groups developed eye itching and eye irritation during the treatment period, but the symptoms were mild and did not affect the follow-up treatment and the results of this study. Conclusion compound Xueshuantong capsule combined with levofloxacin eye drops is effective and safe in the treatment of acute bacterial conjunctivitis. This method can improve the bacterial clearance, accelerate the recovery of patients and improve the clinical efficacy.
【作者单位】： 解放军第一一七医院眼科;解放军第一一七医院心血管内科;
【基金】：浙江省医药卫生科技计划基金资助项目(2013KYA177)
【分类号】：R777.31
，
本文编号：2167421
本文链接：https://www.wllwen.com/yixuelunwen/chuanranbingxuelunwen/2167421.html
最近更新
教材专著
