不同类型冠心病患者心律失常的相关因素
发布时间：2018-10-22 10:54
【摘要】：目的探讨不同类型冠心病患者心律失常发生情况的临床相关因素。方法 1 014例冠心病患者,分为急性冠脉综合征(ACS)和慢性缺血综合征(CIS)两种类型,采用动态心电图检查记录所发生的心律失常类型,分析比较各组中房性心律失常或室性心律失常的发生与年龄、性别、高血压病、糖尿病、高脂血症、冠脉病变支数、血钾、脑尿钠肽(BNP)、左室射血分数(LVEF)和左室舒张末期内径(LVEDD)值的相关性,并通过logistic回归分析,找出心律失常发生情况的相关因素。结果 (1)ACS患者的年龄、性别、高血压、糖尿病、高脂血症、冠脉病变支数、BNP、LVEF及LVEDD值在发生房性或室性心律失常中的差异无统计学意义,而血钾值在发生房性或室性心律失常中的差异有统计学意义(P0.05);logistic回归分析显示,ACS患者发生室性心律失常的独立相关因素是低血钾(P=0.027,OR:2.009,95%CI:1.084-3.726)。(2)CIS患者的年龄、性别、高血压病、糖尿病、高脂血症、冠脉病变支数、血钾值在发生房性或室性心律失常中的差异无统计学意义,而BNP、LVEF及LVEDD值在发生房性或室性心律失常中的差异有统计学意义(P0.05);logistic回归分析显示,CIS患者发生室性心律失常的独立相关因素是LVEF降低(P=0.048,OR:3.561,95%CI:1.010-12.553)。结论低血钾可能是ACS组患者发生室性心律失常的独立相关因素;而LVEF降低可能是CIS组患者发生室性心律失常的独立相关因素。
[Abstract]:Objective to investigate the clinical related factors of arrhythmia in patients with different types of coronary heart disease. Methods 1,014 patients with coronary heart disease were divided into two types: acute coronary syndrome (ACS) and chronic ischemic syndrome (CIS). To compare the incidence of atrial arrhythmia and ventricular arrhythmia with age, sex, hypertension, diabetes mellitus, hyperlipidemia, coronary artery disease, blood potassium, and compare the incidence of atrial arrhythmia and ventricular arrhythmia in each group. The correlation between left ventricular ejection fraction (LVEF) and left ventricular end-diastolic diameter (LVEDD) of brain natriuretic peptide (BNP),) was analyzed by logistic regression analysis. Results (1) there was no significant difference in age, sex, hypertension, diabetes, hyperlipidemia, coronary artery disease branches, BNP,LVEF and LVEDD values in patients with atrial or ventricular arrhythmias. However, there was significant difference in serum potassium levels in patients with atrial or ventricular arrhythmias (P0.05); logistic regression analysis showed that the independent factors associated with ventricular arrhythmias in patients with ACS were the age, sex, hypertension, diabetes mellitus, age, sex, hypertension, diabetes mellitus) of patients with CIS with hypokalemia (P < 0.027): OR: 2.009 / 95CI: 1.084-3.726). (. There was no significant difference in hyperlipidemia, coronary artery disease branches and serum potassium levels in atrial or ventricular arrhythmias. The difference of BNP,LVEF and LVEDD in the occurrence of atrial or ventricular arrhythmias was statistically significant (P0.05); logistic regression analysis showed that the independent factor related to the occurrence of ventricular arrhythmias in CIS patients was the decrease of LVEF (P < 0.048): O: 3.56195 CI: 1.010-12.553). Conclusion hypokalemia may be an independent correlation factor for ventricular arrhythmias in ACS group, while the decrease of LVEF may be an independent correlation factor for ventricular arrhythmia in CIS group.
【作者单位】： 中国医科大学附属第一医院心血管内科;
【基金】：辽宁省社会发展攻关计划项目资助(20122250019)
【分类号】：R514.4
本文编号：2286951
[Abstract]:Objective to investigate the clinical related factors of arrhythmia in patients with different types of coronary heart disease. Methods 1,014 patients with coronary heart disease were divided into two types: acute coronary syndrome (ACS) and chronic ischemic syndrome (CIS). To compare the incidence of atrial arrhythmia and ventricular arrhythmia with age, sex, hypertension, diabetes mellitus, hyperlipidemia, coronary artery disease, blood potassium, and compare the incidence of atrial arrhythmia and ventricular arrhythmia in each group. The correlation between left ventricular ejection fraction (LVEF) and left ventricular end-diastolic diameter (LVEDD) of brain natriuretic peptide (BNP),) was analyzed by logistic regression analysis. Results (1) there was no significant difference in age, sex, hypertension, diabetes, hyperlipidemia, coronary artery disease branches, BNP,LVEF and LVEDD values in patients with atrial or ventricular arrhythmias. However, there was significant difference in serum potassium levels in patients with atrial or ventricular arrhythmias (P0.05); logistic regression analysis showed that the independent factors associated with ventricular arrhythmias in patients with ACS were the age, sex, hypertension, diabetes mellitus, age, sex, hypertension, diabetes mellitus) of patients with CIS with hypokalemia (P < 0.027): OR: 2.009 / 95CI: 1.084-3.726). (. There was no significant difference in hyperlipidemia, coronary artery disease branches and serum potassium levels in atrial or ventricular arrhythmias. The difference of BNP,LVEF and LVEDD in the occurrence of atrial or ventricular arrhythmias was statistically significant (P0.05); logistic regression analysis showed that the independent factor related to the occurrence of ventricular arrhythmias in CIS patients was the decrease of LVEF (P < 0.048): O: 3.56195 CI: 1.010-12.553). Conclusion hypokalemia may be an independent correlation factor for ventricular arrhythmias in ACS group, while the decrease of LVEF may be an independent correlation factor for ventricular arrhythmia in CIS group.
【作者单位】： 中国医科大学附属第一医院心血管内科;
【基金】：辽宁省社会发展攻关计划项目资助(20122250019)
【分类号】：R514.4
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