5例埃博拉病毒病患者的临床特征分析
发布时间：2018-11-07 20:50
【摘要】：目的分析5例埃博拉病毒病(Ebola virus disease,EVD)确诊患者的诊治情况,为更好地防治EVD提供科学依据。方法 2014年12月5日至2015年1月17日在利比里亚中国埃博拉治疗中心(Ebola Treatment Center,ETC)收治5例EVD确诊患者,对其流行病学资料、症状、体征、实验室检查及治疗转归情况进行分析。结果本次确诊的5例患者,其中3例为家庭聚集性发病;有3例患者首次埃博拉病毒核酸检测为阴性,第2次复检为阳性;临床表现以发热、乏力、呕吐、腹泻等为主,少有出血相关症状及体征;通过尽早采取退热、补液等对症、支持治疗,3例患者康复出院,2例死亡。结论对有明确密切接触史但首次埃博拉核酸检测阴性的患者,必须于72 h后复检;治疗上目前仍以对症支持治疗为主,治疗的重点是纠正水、电解质紊乱,维持内环境稳定,预防并发症的发生。
[Abstract]:Objective to analyze the diagnosis and treatment of 5 patients with Ebola virus disease (Ebola virus disease,EVD) and to provide scientific basis for better prevention and treatment of EVD. Methods from December 5, 2014 to January 17, 2015, five patients with EVD were treated in (Ebola Treatment Center,ETC, China Ebola treatment Center in Liberia. The epidemiological data, symptoms and signs were analyzed. Laboratory examination and treatment outcome were analyzed. Results among the 5 confirmed cases, 3 cases were familial agglomeration, 3 cases were negative for Ebola virus nucleic acid for the first time and the second time was positive for Ebola virus nucleic acid, and 3 cases were positive for Ebola virus nucleic acid for the first time. The clinical manifestations were fever, fatigue, vomiting, diarrhea, etc. There were few symptoms and signs associated with hemorrhage, and 3 patients recovered and 2 died after treatment with antipyrexia and fluid rehydration as soon as possible. Conclusion for patients with a clear history of close contact but negative detection of Ebola nucleic acid for the first time, they must be re-examined 72 hours later. At present, the treatment is based on symptomatic support therapy. The focus of treatment is to correct the disturbance of water and electrolyte, to maintain the stability of internal environment and to prevent the occurrence of complications.
【作者单位】： 中国人民解放军首批援利医疗队;第三军医大学西南医院;第三军医大学新桥医院;
【分类号】：R512.8
本文编号：2317536
[Abstract]:Objective to analyze the diagnosis and treatment of 5 patients with Ebola virus disease (Ebola virus disease,EVD) and to provide scientific basis for better prevention and treatment of EVD. Methods from December 5, 2014 to January 17, 2015, five patients with EVD were treated in (Ebola Treatment Center,ETC, China Ebola treatment Center in Liberia. The epidemiological data, symptoms and signs were analyzed. Laboratory examination and treatment outcome were analyzed. Results among the 5 confirmed cases, 3 cases were familial agglomeration, 3 cases were negative for Ebola virus nucleic acid for the first time and the second time was positive for Ebola virus nucleic acid, and 3 cases were positive for Ebola virus nucleic acid for the first time. The clinical manifestations were fever, fatigue, vomiting, diarrhea, etc. There were few symptoms and signs associated with hemorrhage, and 3 patients recovered and 2 died after treatment with antipyrexia and fluid rehydration as soon as possible. Conclusion for patients with a clear history of close contact but negative detection of Ebola nucleic acid for the first time, they must be re-examined 72 hours later. At present, the treatment is based on symptomatic support therapy. The focus of treatment is to correct the disturbance of water and electrolyte, to maintain the stability of internal environment and to prevent the occurrence of complications.
【作者单位】： 中国人民解放军首批援利医疗队;第三军医大学西南医院;第三军医大学新桥医院;
【分类号】：R512.8
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