135例急性血吸虫病例IHA检测抗体滴度效价分析

发布时间：2018-12-28 19:53

【摘要】：目的分析急性血吸虫病确诊病例间接血凝试验(IHA)检测抗体滴度效价,为诊断与治疗急性血吸虫病提供依据。方法以2001年以来收治住院的135例急性血吸虫病确诊病例为观察对象。采集病人基本情况,询问疫水接触情况等,并进行IHA抗体滴度效价检测,比较不同年龄、潜伏期与住院天数之间的相关性。结果 135例病例中IHA检测抗体滴度均1∶320,其中滴度1∶640、1∶1 280、1∶2 560、1∶5 120、1∶10 240分别占1.48%、28.15%、35.56%、20.00%、14.81%。急性感染病例的平均年龄47.70±14.58岁,平均潜伏期38.03±4.59 d,平均住院时间15.08±3.79 d。抗体滴度效价与年龄分布无相关性(r=0.109,P0.05),差异无统计学意义(F=0.64,P0.05),但与潜伏期呈负相关(r=-0.558,P0.01)、住院时间呈正相关(r=0.791,P0.01),各组差异均有统计学意义(F=17.07、64.53,P均0.01)。结论 IHA检测急性血吸虫病例抗体滴度效价均在1∶640及以上,抗体滴度效价与年龄大小无相关性,抗体滴度效价高者,血吸虫病潜伏期短、住院时间长。
[Abstract]:Objective to analyze the titer of antibody detected by indirect hemagglutination test (IHA) in patients with acute schistosomiasis and to provide evidence for diagnosis and treatment of acute schistosomiasis. Methods 135 cases of acute schistosomiasis were treated in our hospital since 2001. The basic data of patients were collected, the contact of infected water was inquired, and the titer of IHA antibody was detected to compare the correlation between different ages, incubation period and hospitalization days. Results in 135 cases, the titer of IHA antibody was 1: 320, of which 1: 640 was 1: 650: 1: 1 280: 1 2 560 1: 5 120 1: 10 240, occupied 1.48% 28.1535.5620.00 and 14.81, respectively. The mean age, latency and hospitalization time of acute infection cases were 47.70 卤14.58 years, 38.03 卤4.59 days and 15.08 卤3.79 days, respectively. There was no correlation between titer of antibody and age distribution (P 0.05), but there was no significant difference between antibody titer and age distribution (P 0.05), but there was a negative correlation between titer of antibody and latency (r P 0.01). P 0.01), the difference was statistically significant in all groups (F = 17.07, P = 64.53, P 0.01). Conclusion the titer of antibody detected by IHA in acute schistosomiasis patients was above 1: 640. There was no correlation between titer of antibody and age. If the titer of antibody was high, the incubation period of schistosomiasis was short and the hospitalization time was long.
【作者单位】：湖北省公安县血吸虫病专科医院;湖北省公安县疾病预防控制中心血吸虫病预防所;
【分类号】：R532.21

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