宁夏男男性行为者HIV新发感染及影响因素分析

发布时间：2019-01-04 10:25

【摘要】：目的了解宁夏男男性行为者的艾滋病病毒新发感染情况,并分析其影响因素及队列保持情况,为决策提供建议。方法采用前瞻性开放性队列研究方法,2011年4-6月建立队列,6个月及12个月后分别随访,问卷调查收集社会人口学、行为学等信息和艾滋病病毒检测情况。艾滋病新发感染率的影响因素采用COX回归分析。结果剔除本底招募中的18例艾滋病病毒抗体阳性,共调查符合条件的男男性行为者726例。随访组309例中,艾滋病病毒新发感染率为2.90/100人年(95%CI:1.45~5.80)。多因素分析艾滋病病毒新发感染的危险因素为近6个月4个以上性伴(HR=13.82,95%CI:6.55~24.10),保护因素为近1年接受过咨询检测(HR=0.04,95%CI:0.01~0.15)。肛交时使用安全套,接受艾滋病相关服务随访者较脱失者高。脱失人群未婚或离异的比例较高(P0.05)。结论宁夏男男性行为人群中HIV发病率较发达地区低,存在不安全性行为,随访人群接受干预的比例较脱失人群高。应加大检测咨询为主的综合干预措施,遏制艾滋病在该人群的传播。
[Abstract]:Objective to investigate the status of new HIV infection among men who have sex with men in Ningxia and analyze its influencing factors and cohort maintenance. Methods A prospective open cohort study was used. The cohort was set up from April to June 2011, followed up after 6 months and 12 months respectively. The information of social demography, behavior and HIV detection were collected by questionnaire. COX regression analysis was used to analyze the influencing factors of new AIDS infection rate. Results A total of 726 eligible men who had sex with men were investigated. In the follow-up group of 309 cases, the new HIV infection rate was 2.90 / 100 person-years (95%CI:1.45~5.80). Multivariate analysis showed that the risk factors of new HIV infection were more than 4 sexual partners (HR=13.82,95%CI:6.55~24.10) in the last 6 months, and the protective factors were counseling and testing (HR=0.04,95%CI:0.01~0.15) in the past 1 year. Anal use of condoms, AIDS-related services to follow-up than the loss of the higher. The proportion of unmarried or divorced group was higher (P0.05). Conclusion the incidence of HIV in men with sex with men in Ningxia is lower than that in developed areas, and there is unsafe sex. The proportion of intervention in the follow-up population is higher than that in the lost population. We should increase the comprehensive intervention measures based on testing counseling to curb the spread of AIDS in this population.
【作者单位】：宁夏自治区疾病预防控制中心;
【基金】：中美艾滋病防治合作项目(2011-2012-宁夏-10)~~
【分类号】：R512.91

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